Pleiotropic Effects of ebony and tan on Pigmentation and Cuticular Hydrocarbon Composition in Drosophila melanogaster
Pleiotropic Effects of ebony and tan on Pigmentation and Cuticular Hydrocarbon Composition in Drosophila melanogaster
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DOI：
10.3389/fphys.2019.00518
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发表时间：
2019-05-01
影响因子：
4
通讯作者：
Takahashi, Aya
中科院分区：
文献类型：
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作者：
Massey, Jonathan H.;Akiyama, Noriyoshi;Takahashi, Aya
多效性基因是影响一个以上性状的基因。例如，果蝇（Drosophila melanogaster）色素沉着所需的许多基因也会影响昼夜节律、视觉和交配行为等性状。在这里，我们提出的证据表明，两个色素沉着基因，乌木和谭，编码酶催化黑色素生物合成途径中的相互反应，也影响角质碳氢化合物（CHC）组成的D。melanogaster雌性更具体地说，我们报告说，乌木功能丧失突变体的CHC谱偏向长链（> 25 C）CHC，而棕褐色功能丧失突变体的CHC谱偏向短链（> 25 C）CHC。
Pleiotropic genes are genes that affect more than one trait. For example, many genes required for pigmentation in the fruit fly Drosophila melanogaster also affect traits such as circadian rhythms, vision, and mating behavior. Here, we present evidence that two pigmentation genes, ebony and tan, which encode enzymes catalyzing reciprocal reactions in the melanin biosynthesis pathway, also affect cuticular hydrocarbon (CHC) composition in D. melanogaster females. More specifically, we report that ebony loss-of-function mutants have a CHC profile that is biased toward long (>25C) chain CHCs, whereas tan loss-of-function mutants have a CHC profile that is biased toward short (