JLIN: a java based linkage disequilibrium plotter.
JLIN: a java based linkage disequilibrium plotter.
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JLIN：基于Java的连锁不平衡绘图仪。
DOI：
10.1186/1471-2105-7-60
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发表时间：
2006-02-09
影响因子：
3
通讯作者：
中科院分区：
文献类型：
--
作者：
国际上正在花费大量的精力和费用，试图检测导致复杂人类疾病易感性的基因多态。连锁不平衡作图等技术正越来越多地被用于检查和比较日益庞大的数据集上的标记。可视化技术正在成为分析任何给定分析所能获得的不断增长的数据量和结果的关键。JLIN(Java链接不平衡绘图仪)是一个软件包，用于定制、直观地显示所有常见计算平台上的链接不平衡(LD)。定制允许用户选择特定的可视化、统计测量和测量范围。Jlin还允许用户以几种常见的文档格式导出LD可视化图像。JLIN允许用户直观地比较和对比输入数据集上的一系列统计测量的结果(S)。这些衡量标准包括常用的D‘和R2统计量以及经验p值。Jlin有许多独特和新颖的功能，这些功能改进了现有的LD可视化工具。
A great deal of effort and expense are being expended internationally in attempts to detect genetic polymorphisms contributing to susceptibility to complex human disease. Techniques such as Linkage Disequilibrium mapping are being increasingly used to examine and compare markers across increasingly large datasets. Visualisation techniques are becoming essential to analyse the ever-growing volume of data and results available with any given analysis. JLIN (Java LINkage disequilibrium plotter) is a software package designed for customisable, intuitive visualisation of Linkage Disequilibrium (LD) across all common computing platforms. Customisation allows the user to choose particular visualisations, statistical measures and measurement ranges. JLIN also allows the user to export images of the LD visualisation in several common document formats. JLIN allows the user to visually compare and contrast the results of a range of statistical measures on the input dataset(s). These measures include the commonly used D' and r2 statistics and empirical p-values. JLIN has a number of unique and novel features that improve on existing LD visualisation tools.