Too Much Sitting and Cardio-Metabolic Risk: An Update of Epidemiological Evidence
Too Much Sitting and Cardio-Metabolic Risk: An Update of Epidemiological Evidence
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DOI：
10.1007/s12170-013-0316-y
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发表时间：
2013-08-01
影响因子：
1.9
通讯作者：
Bennie, Jason
中科院分区：
文献类型：
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作者：
Bauman, Adrian E.;Chau, Josephine Y.;Bennie, Jason
久坐行为与缺乏中度到剧烈的身体活动不同，是一种新兴的慢性疾病发展的健康风险行为。久坐行为的例子包括坐着、看电视、使用电脑和开车。在这篇文章中，我们定义了久坐行为;概述了与久坐行为生理学相关的关键概念，回顾了长期久坐行为（或坐着）对心脏代谢疾病和全因死亡风险影响的最新证据，并讨论了对当前临床实践的影响。我们发现，大多数关于久坐行为的大规模研究都是在过去5年中发表的。有适度一致的证据表明，总坐着的时间和全因死亡率之间的关联，即使调整或分层的休闲时间体力活动。总的来说，我们确定了一个令人信服的案例，将减少坐姿纳入临床预防建议，作为“积极生活”的关键组成部分，鼓励成人和儿童在一天中在不同的环境和地点“多动少坐”。
Sedentary behavior, as distinct from a lack of moderate-to-vigorous physical activity, is an emerging health risk behavior for the development of chronic diseases. Examples of sedentary behavior include sitting, watching television, using a computer, and driving a car. In this article, we define sedentary behavior; outline key concepts related to the physiology of sedentary behavior, review the recent evidence on the effects of prolonged sedentary behavior (or sitting) on the risk of cardio-metabolic disease and all cause mortality, and discuss the implications for current clinical practice. We found that most large scale studies on sedentary behavior were published in the last 5 years. There is moderately consistent evidence for an association between total sitting time and all-cause mortality, even when adjusted for or stratified by leisure time physical activity. Overall, we identified a compelling case for sitting reduction to be included in clinical preventive advice as a key component of 'active living,' where adults and children are encouraged to 'move more and sit less' across different settings and locations throughout the day.