Executive Control in Depressive Rumination: Backward Inhibition and Non-inhibitory Switching Performance in a Modified Mixed Antisaccade Task.
Executive Control in Depressive Rumination: Backward Inhibition and Non-inhibitory Switching Performance in a Modified Mixed Antisaccade Task.
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DOI：
10.3389/fpsyg.2017.00136
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发表时间：
2017
影响因子：
3.8
通讯作者：
Liu JC
中科院分区：
文献类型：
--
作者：
Lo BC;Liu JC
背景和目标：本研究考察了抑郁和健康被试在一个改进的混合反跳任务中的后向抑制（BI）和非抑制转换表现。具体而言，悲伤和中性的面孔被纳入设计，以检查与沉思特质相关的执行控制困难。方法：39名被试参加了研究，其中抑郁症患者19名，健康对照组20名。参与者完成了诊断性访谈和自我报告问卷，包括贝克抑郁量表和反刍反应量表-沉思子量表。然后，他们被指示在纯块和混合块中完成前视和反视试验，从而跟踪眼睛注视以评估抑制和转换效率。结果如下：在转换效应方面，采用多水平模型分析发现，存在显著的群体×沉思×任务类型交互作用。当悲伤的面孔呈现给抑郁组时，与沉思相关的转换缺陷被发现是最大的。未观察到BI或错误率的显著结果。结论：所观察到的模式表明，相对于BI，与沉思特质相关的设置转换困难可能会受到负面情绪和认知的调节。在未来的研究中，除了悲伤的面孔之外，情绪面孔可能会被用来进一步探索观察结果是否可以推广到其他情感条件。
Background and Objectives: The present study examines backward inhibition (BI) and non-inhibitory switching performance among depressed and healthy participants in a modified mixed antisaccade task. Specifically, sad and neutral faces were incorporated in the design to examine executive control difficulties associated with brooding trait. Methods: Thirty-nine participants took part in the study, including 19 depressed patients and 20 healthy control subjects. Participants completed a diagnostic interview and self-report questionnaires, including the Beck Depression Inventory and Ruminative Response Scale-Brooding Subscale. They were then instructed to complete prosaccade and antisaccade trials in the pure and mixed blocks whereby eye gazes were tracked to assess inhibition and switching efficiency. Results: For the switching effects, a significant group × brooding × task type interaction was found as hypothesized when multilevel modeling analysis was employed. Switching deficits associated with brooding was found to be greatest when sad faces were presented to depressed group. No significant results in BI or error rates were observed. Conclusion: The patterns observed suggest that as opposed to BI, set shifting difficulty associated with brooding trait may be modulated by negative mood and cognition. In future research, emotional faces other than sad faces may be used to further explore if the observations could be generalized to other affective conditions.