Utility of ultrasound and fine-needle aspiration biopsy of the axilla in the assessment of invasive lobular carcinoma of the breast
Utility of ultrasound and fine-needle aspiration biopsy of the axilla in the assessment of invasive lobular carcinoma of the breast
复制标题
DOI：
10.1016/j.amjsurg.2007.06.017
复制
发表时间：
2007-10-01
影响因子：
3
通讯作者：
Bedrosian, Isabelle
中科院分区：
文献类型：
--
作者：
Boughey, Judy C.;Middleton, Lavinia P.;Bedrosian, Isabelle
背景：浸润性小叶癌（ILC）独特的生长模式对术前评估乳腺内病变程度提出了挑战。它是否同样限制了超声（US）和细针穿刺（FNA）活检的淋巴结分期是当前研究的主题。方法：对217例接受腋窝超声检查的ILC患者进行回顾性分析。当超声检查结果可疑或不确定时，进行FNA活检。结果与文献报道的浸润性导管癌（IDC）患者的超声检查结果进行了比较。结果：腋窝超声阴性137例（63%），可疑或不确定80例（37%）。62%（47/76）患者FNA活检呈阳性。术前US和FNA活检发现111例淋巴结阳性患者中的43例（39%）。FNA活检US的敏感性与原发肿瘤和淋巴结转移大小相关。在IDC人群中也看到了类似的结果。结论：US与FNA活检在ILC和IDC患者的腋窝分期中似乎同样有用。(c) 2007年摘录医药有限公司版权所有。
Background: The unique growth pattern of invasive lobular carcinoma (ILC) poses a challenge for preoperative assessment of disease extent within the breast. Whether it similarly limits lymph node staging by ultrasound (US) and fine-needle aspiration (FNA) biopsy was the subject of the current study.Methods: A total of 217 patients with ILC who underwent axillary US were reviewed. FNA biopsy was performed when US findings were suspicious or indeterminate. Findings were compared to literature reports of US in invasive ductal carcinoma (IDC) patients.Results: Axillary US was negative in 137 patients (63%) and suspicious or indeterminate in 80 patients (37%). FNA biopsy was positive in 62% (47/76 patients). Preoperative US and FNA biopsy identified 43 of 111 (39%) node-positive patients. Sensitivity of US with FNA biopsy correlated with primary tumor and nodal metastasis size. Similar results were seen in IDC populations.Conclusion: US with FNA biopsy appears to be similarly useful in axillary staging of ILC and IDC patients. (c) 2007 Excerpta Medica Inc. All rights reserved.