Orofacial granulomatosis associated with delayed hypersensitivity to cobalt
Orofacial granulomatosis associated with delayed hypersensitivity to cobalt
复制标题
与钴迟发型超敏反应相关的口面部肉芽肿病
DOI：
10.1111/j.1365-2230.1990.tb02123.x
复制
发表时间：
1990
影响因子：
4.1
通讯作者：
C. King
中科院分区：
文献类型：
--
作者：
D. Pryce;C. King
口面部肉芽肿病是一种独特的临床和病理实体，其特征在于嘴唇和面部下厅肿胀，也可发生口腔粘膜溃疡。组织学上可见肉芽肿。口面部肉芽肿病可发生在Melkersonn-Rosenthal综合征、Miescher肉芽肿性唇炎、口腔克罗恩病、结节病和局灶性牙脓毒症中。口面肉芽肿患者中特应性的患病率增加以及与食物不耐受的相关性表明至少在某些情况下过敏可能起作用。
Orofacial granulomatosis is a distinct clinical and pathological entity characterised by swelling of the lips and lower hall of the face, Ulceration of the oral mucosa may also occur. Granulomas are seen histologically. Orofacial granulomatosis may occur in the Melkerssonn–Rosenthal syndrome, granulomatous cheilitis of Miescher, oral Crohn's disease, sarcoidosis and focal dental sepsis. The increased prevalence of atopy in patients with orofacial granulomatosis and the association with food intolerance suggests the possibility of a role for allergy in at least some cases.