Age and sex analyses of out-of-hospital cardiac arrest in Osaka, Japan
Age and sex analyses of out-of-hospital cardiac arrest in Osaka, Japan
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DOI：
10.1016/s0300-9572(03)00035-2
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发表时间：
2003-05-01
期刊：
影响因子：
6.5
通讯作者：
Sugimoto, H
中科院分区：
文献类型：
--
作者：
Iwami, T;Hiraide, A;Sugimoto, H
目的：分析院外心脏骤停患者按年龄、性别的分布特点，特别是室颤(VF)，以确定院外心脏骤停有效的干预靶点。方法：对日本大阪府2年内发生院外心脏骤停的患者按Utstein方式进行前瞻性记录。按年龄和性别评价逮捕、目击逮捕、室性早搏病例的数量和发生率。还计算了逮捕案件中复苏尝试的百分比。结果：我们连续记录了10139例院外心脏骤停。在10139人中，97.0%的人尝试了复苏，年龄和性别之间没有显著差异。心脏骤停的发生率随着年龄的增长呈指数增长。在各个年龄段中，男性的院外逮捕发生率明显高于女性。大多数目睹的室颤病例显示心脏病因，主要发生在50多岁、60多岁和70多岁的男性。亲眼室颤的发生率也较高。结论：我们的研究提供了证据，表明心脏骤停在年龄和性别方面存在显著的流行病学差异，我们需要更好地了解这些差异。应该采取以高产出患者为重点的策略，即那些目睹了室颤的患者。这些努力应该预期会在幸存者中产生与性别和年龄相关的差异。(C)2003爱思唯尔爱尔兰科学有限公司。保留所有权利。
Objective: To determine effective interventional targets for out-of-hospital cardiac arrests by analyzing the distribution characteristics of arrest patients according to age and sex with special emphasis on ventricular fibrillation (VF). Methods: All patients who suffered out-of-hospital cardiac arrest in Osaka Prefecture, Japan during 2 years, were prospectively recorded based on the Utstein style. The number and the incidence rate of cases of arrest, witnessed arrest, and witnessed VF were evaluated according to age and sex. The percentage of resuscitation attempts in arrest cases was also calculated. Results: We recorded 10 139 consecutive out-of-hospital cardiac arrest cases. Resuscitation was attempted in 97.0% of 10 139 and showed no significant differences by age and sex. The incidence rate of cardiac arrests increased exponentially with age. Men showed a significantly higher incidence rate of out-of-hospital arrests than women in every age group. Most of the witnessed VF cases showed cardiac aetiology and were predominantly observed in men in their 50s, 60s and 70s. The incidence rates of witnessed VF were also greater in them. Conclusion: Our study provides evidence that there are significant age and sex related epidemiological differences in cardiac arrests and we need to understand them better. Strategies that focus on high yielded patients, those in witnessed VF, should be pursued. These efforts should be expected to yield sex and age related differences in survivors. (C) 2003 Elsevier Science Ireland Ltd. All rights reserved.