Phthalates in indoor dust and their association with building characteristics.
Phthalates in indoor dust and their association with building characteristics.
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DOI：
10.1289/ehp.7809
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发表时间：
2005-10
影响因子：
10.4
通讯作者：
Sundell, Jan
中科院分区：
文献类型：
--
作者：
Bornehag, Carl-Gustaf;Lundgren, Bjorn;Weschler, Charles J;Sigsgaard, Torben;Hagerhed-Engman, Linda;Sundell, Jan
在最近的一项研究中，198名瑞典儿童持续过敏症状和202名对照没有这样的症状，我们报告了症状和邻苯二甲酸正丁基苄酯（BBzP）和邻苯二甲酸二（2-乙基己基）酯（DEHP）的浓度之间的关联从孩子们的卧室采取的灰尘。在本研究中，我们研究了不同的邻苯二甲酸酯的浓度之间的关联，从这些卧室和家庭的各种特征的灰尘。该研究重点关注BBzP和DEHP，因为这些是与健康投诉相关的邻苯二甲酸酯。使用参数和非参数检验以及多元logistic回归分析了相关性。对于BBzP和DEHP，我们发现它们的粉尘浓度与家庭中用作地板和墙壁材料的聚氯乙烯（PVC）数量之间存在关联。此外，高浓度的BBzP（高于中位数）与家庭中自我报告的漏水有关，高浓度的DEHP与1960年以前建造的建筑物有关。据报告，还有其他协会，也有没有协会的情况。BBzP和DEHP都在既没有PVC地板也没有墙面覆盖物的建筑物中发现，这与预期在典型家庭中存在的许多其他增塑材料一致。在这项研究中检查的建筑特征不能作为这些相当不同的来源的完整代理。然而，这里报告的协会可以帮助确定邻苯二甲酸酯浓度可能升高的家庭，并有助于制定缓解策略。
In a recent study of 198 Swedish children with persistent allergic symptoms and 202 controls without such symptoms, we reported associations between the symptoms and the concentrations of n-butyl benzyl phthalate (BBzP) and di(2-ethylhexyl) phthalate (DEHP) in dust taken from the childrens’ bedrooms. In the present study we examined associations between the concentrations of different phthalate esters in the dust from these bedrooms and various characteristics of the home. The study focused on BBzP and DEHP because these were the phthalates associated with health complaints. Associations have been examined using parametric and nonparametric tests as well as multiple logistic regression. For both BBzP and DEHP, we found associations between their dust concentrations and the amount of polyvinyl chloride (PVC) used as flooring and wall material in the home. Furthermore, high concentrations of BBzP (above median) were associated with self-reported water leakage in the home, and high concentrations of DEHP were associated with buildings constructed before 1960. Other associations, as well as absence of associations, are reported. Both BBzP and DEHP were found in buildings with neither PVC flooring nor wall covering, consistent with the numerous additional plasticized materials that are anticipated to be present in a typical home. The building characteristics examined in this study cannot serve as complete proxies for these quite varied sources. However, the associations reported here can help identify homes where phthalate concentrations are likely to be elevated and can aid in developing mitigation strategies.