Video Head Impulse Test (vHIT): The Role of Corrective Saccades in Identifying Patients With Vestibular Loss.
Video Head Impulse Test (vHIT): The Role of Corrective Saccades in Identifying Patients With Vestibular Loss.
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DOI：
10.1097/mao.0000000000001751
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发表时间：
2018-04
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影响因子：
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通讯作者：
Honaker JA
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文献类型：
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作者：
Janky KL;Patterson J;Shepard N;Thomas M;Barin K;Creutz T;Schmid K;Honaker JA
目的：1）描述正常对照组的矫正性扫视（CS）特征，2）检测视频头部脉冲测试（vHIT）对使用增益和CS识别前庭功能丧失的敏感性。研究设计：前瞻性结合回顾性研究。设置：三级转诊中心。患者：70例前庭功能正常的受试者作为对照（平均年龄44.1岁，范围10-78岁）和49例单侧和双侧前庭丧失患者的资料进行了回顾性分析（平均年龄，50;范围，7-81）.干预：vHIT;然后在MATLAB中分析个体水平头部冲动。主要结果测量：水平vHIT增益、CS峰值速度、频率和潜伏期。增益和CS潜伏期是受脉冲侧影响的唯一参数，表明右侧的增益更高，潜伏期更长。与对照组相比，前庭功能丧失组的平均vHIT增益显著降低，平均CS频率显著升高，平均CS速度显著升高，CS潜伏期显著提前，平均CS潜伏期标准差显著减小。
Objective:1) Characterize corrective saccades (CS) in normal controls, and 2) examine the sensitivity of the video head impulse test (vHIT) for identifying vestibular loss using both gain and CS.Study Design:Prospective combined with retrospective review.Setting:Tertiary referral center.Patients:Seventy subjects with normal vestibular function served as controls (mean age, 44.1 yr; range, 10–78) and data from 49 patients with unilateral and bilateral vestibular loss was retrospectively reviewed (mean age, 50; range, 7–81).Intervention:vHIT; individual horizontal head impulses were then analyzed in MATLAB.Main Outcome Measures:Horizontal vHIT gain, CS peak velocity, frequency, and latency.Results:There was not an age effect for CS velocity or latency, and only a weak relationship between CS frequency and age in the control group. Gain and CS latency were the only parameters affected by impulse side, demonstrating higher gain and longer latency on the right. The group with vestibular loss had significantly lower mean vHIT gain, higher mean CS frequency, higher mean CS velocity, earlier CS latency, and smaller mean CS standard deviations of the latency compared with the control group.