The digital code of DNA
The digital code of DNA
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DOI：
10.1038/nature01410
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发表时间：
2003-01-23
期刊：
影响因子：
64.8
通讯作者：
Galas, D
中科院分区：
文献类型：
--
作者：
Hood, L;Galas, D
DNA结构的发现深刻地改变了生物学，催化了人类基因组的测序，并产生了生物学作为信息科学的新观点。DNA结构的两个特征在很大程度上解释了它对科学的显著影响：它的数字性质和互补性，即螺旋的一条链与它的伴侣完美结合。DNA有两种类型的数字信息-编码蛋白质的基因，这是生命的分子机器，以及指定基因行为的基因调控网络。
The discovery of the structure of DNA transformed biology profoundly, catalysing the sequencing of the human genome and engendering a new view of biology as an information science. Two features of DNA structure account for much of its remarkable impact on science: its digital nature and its complementarity, whereby one strand of the helix binds perfectly with its partner. DNA has two types of digital information - the genes that encode proteins, which are the molecular machines of life, and the gene regulatory networks that specify the behaviour of the genes.