THE INVERSE RELATION BETWEEN FISH CONSUMPTION AND 20-YEAR MORTALITY FROM CORONARY HEART-DISEASE
THE INVERSE RELATION BETWEEN FISH CONSUMPTION AND 20-YEAR MORTALITY FROM CORONARY HEART-DISEASE
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DOI：
10.1056/nejm198505093121901
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发表时间：
1985-01-01
影响因子：
158.5
通讯作者：
COULANDER, CD
中科院分区：
文献类型：
--
作者：
KROMHOUT, D;BOSSCHIETER, EB;COULANDER, CD
格陵兰爱斯基摩人冠心病死亡率低是因为他们吃鱼多。在荷兰祖特芬镇的一组男性中，研究了鱼类消费与冠心病之间的关系。1960年，通过从参与者及其妻子那里获得的仔细的饮食史，收集了852名没有冠心病的中年男性的鱼类消费信息。在20年的随访中，78名男性死于冠心病。在1960年的鱼类消费量和20年的随访期间死于冠心病之间观察到了一种反向的剂量反应关系。这种关系持续多元逻辑回归分析后。每天至少食用30克鱼的人，冠心病死亡率比不吃鱼的人低50%以上。每周食用1至2次鱼菜可能对冠心病有预防价值。
The low death rate from coronary heart disease among the Greenland Eskimos is ascribed to their high fish consumption. The relationship between fish consumption and coronary heart disease was investigated in a group of men in the town of Zutphen, the Netherlands. Information about the fish consumption of 852 middle-aged men without coronary heart disease was collected in 1960 by a careful dietary history obtained from the participants and their wives. During 20 yr of follow-up 78 men died from coronary heart disease. An inverse dose-response relation was observed between fish consumption in 1960 and death from coronary heart disease during 20 yr of follow-up. This relation persisted after multiple logistic-regression analyses. Mortality from coronary heart disease was > 50% lower among those who consumed at least 30 g of fish per day than among those who did not eat fish. The consumption of as little as 1 or 2 fish dishes per week may be of preventive value in relation to coronary heart disease.