Gold nanorods 3D-supercrystals as surface enhanced Raman scattering spectroscopy substrates for the rapid detection of scrambled prions
Gold nanorods 3D-supercrystals as surface enhanced Raman scattering spectroscopy substrates for the rapid detection of scrambled prions
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DOI：
10.1073/pnas.1016530108
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发表时间：
2011-05-17
影响因子：
11.1
通讯作者：
Liz-Marzan, Luis M.
中科院分区：
文献类型：
--
作者：
Alvarez-Puebla, Ramon A.;Agarwal, Ashish;Liz-Marzan, Luis M.
具有电场增强的等离子体天线的高度组织化的Au纳米棒的超晶体使得在复杂的生物介质（例如血清和血液）中快速直接检测朊病毒成为可能。纳米棒的近乎完美的三维组织使这些系统成为具有均匀电场增强的优异表面增强拉曼散射光谱基底，从而在期望的光谱范围内产生可再现的高增强因子。
Highly organized supercrystals of Au nanorods with plasmonic antennae enhancement of electrical field have made possible fast direct detection of prions in complex biological media such as serum and blood. The nearly perfect three-dimensional organization of nanorods render these systems excellent surface enhanced Raman scattering spectroscopy substrates with uniform electric field enhancement, leading to reproducibly high enhancement factor in the desirable spectral range.