Learning from the Fly Photoreceptor on How Synapses Integrate Gene Expression to Sustain Retina and Brain Function.
Learning from the Fly Photoreceptor on How Synapses Integrate Gene Expression to Sustain Retina and Brain Function.
复制标题
从苍蝇感光器中学习突触如何整合基因表达来维持视网膜和大脑功能。
DOI:
10.1016/j.neuron.2019.02.004
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发表时间:
2019
期刊:
影响因子:
16.2
通讯作者:
Gordon,WilliamC
中科院分区:
文献类型:
--
作者:
Bazan,NicolasG;Gordon,WilliamC
Synapse dysfunction is thought to contribute to neurodegenerative diseases. In this issue ofNeuron, Tsai et al. (2019) uncover how membrane phospholipid biosynthesis regulatesDrosophilaphotoreceptor (PR) degeneration and the synaptic vesicle pool through a transcriptional-translational feedback loop from the synaptic terminal to the nucleus.