RESIDENCE NEAR HIGH-VOLTAGE FACILITIES AND RISK OF CANCER IN CHILDREN
RESIDENCE NEAR HIGH-VOLTAGE FACILITIES AND RISK OF CANCER IN CHILDREN
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DOI：
10.1136/bmj.307.6909.891
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发表时间：
1993-10-09
影响因子：
--
通讯作者：
SCHULGEN, G
中科院分区：
文献类型：
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作者：
OLSEN, JH;NIELSEN, A;SCHULGEN, G
研究出生前后居住在50 Hz高压装置附近是否会增加儿童患癌症的风险，以及风险是否与磁场强度相关。设计-一项基于人群的病例对照研究。背景-丹麦。受试者-1707名15岁以下患有白血病、中枢神经系统肿瘤、或恶性淋巴瘤诊断于1968-86年和4788名儿童从中央人口登记处。主要结果测量-出生前和出生后的接近现有或以前的50-400 kV输电连接和变电站和相关的历史电磁场计算的基础上的电流负载线，相排序的线，和距离住宅。结果之间的所有主要类型的儿童癌症合并和暴露于磁场从高压装置大于或等于0.4 μ T（比值比5.6）的显着关联。在大于或等于0.25 μ T时，未观察到显著相关性（比值比1.5）。一个可能的关联也被认为是与霍奇金病的情况下，分别在大于或等于0.1 μ T。结论这些结果和额外的描述性数据的基础上，自20世纪40年代以来，在丹麦的电力消耗和儿童癌症的发病率，得出的结论是，儿童癌症的比例可能引起的50赫兹电磁场必须是小的。
Objective-To investigate whether residence before and after birth near 50 Hz high voltage installations increases a child's risk of cancer and whether risk correlates with the strength of the magnetic field.Design-A population based case-control study.Setting-Denmark.Subjects-1707 children under the age of 15 with leukaemia, tumour of the central nervous system, or malignant lymphoma diagnosed in 1968-86 and 4788 children taken from the central population register.Main outcome measures-Proximity before and after birth to existing or former 50-400 kV electrical transmission connections and substations and associated historical electromagnetic fields calculated on the basis of current load on line, phase ordering of line, and distance from the dwelling.Results-A significant association was seen between all major types of childhood cancer combined and exposure to magnetic fields from high voltage installations of greater-than-or-equal-to 0.4 muT (odds ratio 5.6). At greater-than-or-equal-to 0.25 muT no significant association was seen (odds ratio 1.5). A possible association was also seen with cases of Hodgkin's disease separately at greater-than-or-equal-to 0.1 muT.Conclusion-On the basis these results and additional descriptive data on electricity consumption and incidence of childhood cancer in Denmark since the 1940s it was concluded that the proportion of childhood cancer possibly caused by 50 Hz electromagnetic fields must be small.