Quality improvement of acoustic-resolution photoacoustic imaging of skin vasculature based on practical synthetic-aperture focusing and bandpass filtering
Quality improvement of acoustic-resolution photoacoustic imaging of skin vasculature based on practical synthetic-aperture focusing and bandpass filtering
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DOI：
10.7567/jjap.57.127001
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发表时间：
2018-11
影响因子：
1.5
通讯作者：
Y. Tsunoi;Kenichi Yoshimi;Ryota Watanabe;N. Kumai;M. Terakawa;Shunichi Sato
中科院分区：
文献类型：
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作者：
Y. Tsunoi;Kenichi Yoshimi;Ryota Watanabe;N. Kumai;M. Terakawa;Shunichi Sato
我们以前开发了一个紧凑的声学分辨率光声（PA）成像系统与光纤为基础的照明，在大鼠皮肤血管可视化在体内。然而，在成像特性方面存在有待改进的问题：超声传感器的离焦区域模糊，以及PA信号中的低频分量导致的分辨率下降。这些是声学分辨率PA成像方法中的常见限制。在这项研究中，我们试图解决这些问题，通过引入信号处理方法的基础上的合成孔径聚焦技术，这是只适用于在水平方向的传感器的检测区域中的信号，这是预先确定的幻影研究，和数字声信号滤波与三个特定的频带。大鼠皮肤和皮下组织血管的离体和在体PA成像表明了本信号处理方法的有效性。
We previously developed a compact acoustic-resolution photoacoustic (PA) imaging system with optical fiber-based illumination, by which blood vessels in the rat skin were visualized in vivo. However, there were issues to be improved in the imaging characteristics: blurring in the out-of-focus region of the ultrasound sensor and degraded resolution due to low-frequency components in the PA signals. These are common limitations in acoustic-resolution PA imaging methods. In this study, we attempted to solve these problems by introducing signal processing methods based both on the synthetic-aperture focusing technique, which was applied only to signals in the detection zone of the sensor in the horizontal direction that was determined in advance in a phantom study, and on digital acoustic signal filtering with three specific frequency bands. Ex vivo and in vivo PA imaging of blood vessels in the rat skin and subcutaneous tissue showed the validity of the present signal processing methods.