Polyacrylamid/silver composite particles produced via microfluidic photopolymerization for single particle-based SERS microsensorics.
Polyacrylamid/silver composite particles produced via microfluidic photopolymerization for single particle-based SERS microsensorics.
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DOI：
10.1021/ac302751t
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发表时间：
2013-01
影响因子：
7.4
通讯作者：
J. Köhler;Anne März;J. Popp;A. Knauer;I. Kraus;J. Faerber;C. Serra
中科院分区：
文献类型：
--
作者：
J. Köhler;Anne März;J. Popp;A. Knauer;I. Kraus;J. Faerber;C. Serra
采用微连续流工艺制备了含银纳米颗粒的可溶胀聚丙烯酰胺颗粒。这些传感器粒子是由银纳米粒子和单体的胶体溶液混合而成的，通过基于液滴的过程，原位光引发聚合，随后批量执行银。所得聚合物复合粒子具有较强的表面增强拉曼散射效应。利用单个传感器粒子，腺嘌呤水溶液的特征拉曼信号可以检测到0.1μM。选择的例子表明，复合颗粒适合于高动态范围(腺嘌呤的3个数量级)的定量微量分析程序。
A micro-continuous-flow process was applied for the preparation of swellable polyacrylamide particles incorporating silver nanoparticles. These sensor particles are formed from a mixture of a colloidal solution of silver nanoparticles and monomer by a droplet-based procedure with in situ photoinitiation of polymerization and a subsequent silver enforcement in batch. The obtained polymer composite particles show a strong SERS effect. Characteristic Raman signals of aqueous solutions of adenine could be detected down to 0.1 μM by the use of single sensor particles. The chosen example demonstrates that the composite particles are suitable for quantitative microanalytical procedures with a high dynamic range (3 orders of magnitude for adenine).