"Send this patient's tumor for culture and sensitivity".
"Send this patient's tumor for culture and sensitivity".
复制标题
“将该患者的肿瘤送去进行培养和敏感性分析”。
DOI：
10.1056/nejm198301203080310
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发表时间：
1983
期刊：
影响因子：
--
通讯作者：
D. V. Von Hoff
中科院分区：
文献类型：
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作者：
D. V. Von Hoff
照顾恶性疾病患者的主要目标之一是提供一种治疗方案，使生存机会最大化，并使治疗的副作用最小化。这个目标在癌症化疗中尤为重要。1978年，萨蒙和他的同事报告了一项新的体外试验，用于确定个体患者的肿瘤对抗癌药物的敏感性或耐药性。为了进行现在被称为人类肿瘤干细胞试验的试验，从患者身上取出肿瘤，制成单细胞悬浮液，在体外暴露于抗癌药物中，然后培养。
One of the primary goals in caring for patients with malignant disease is to provide a treatment program that maximizes the chance of survival and minimizes the side effects of therapy. This goal is particularly important in chemotherapy for cancer.In 1978, Salmon and colleagues1reported a new in vitro test for determining the sensitivity or resistance of an individual patient's tumor to an anticancer drug. To perform the test, now called the human tumor stem-cell assay, tumor is removed from the patient, made into a suspension of single cells, exposed to the anticancer drug in vitro, and then cultured . . .