Evaluating Translational Research: A Process Marker Model

Evaluating Translational Research: A Process Marker Model
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DOI:
10.1111/j.1752-8062.2011.00291.x
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发表时间:
2011-06-01
影响因子:
3.9
通讯作者:
Pincus, Harold A.
Pincus, Harold A.
中科院分区:
医学3区
文献类型:
--
作者:
Trochim, William;Kane, Cathleen;Pincus, Harold A.

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目的:我们从负责评估翻译努力的评估者的角度来审视翻译研究的概念。参与转化性研究的评估者的主要任务之一是帮助评估旨在减少将研究转化为实践和对健康影响所需时间的努力。另一项是评估旨在提高翻译速度和数量的努力。方法:我们提供了一种替代主导的当代趋势,即用一系列离散的“阶段”来定义翻译研究。结果:我们认为,这种阶段性方法令人困惑,不足以作为评价的基础。相反,我们主张沿着从研究到实践的一般过程路径确定关键的可操作和可测量的标记。结论:该模型为评估旨在改善翻译研究的干预措施以及将这些发现整合到翻译研究领域提供了基础。《临床医学杂志》2011年第4卷:153-162
Objective: We examine the concept of translational research from the perspective of evaluators charged with assessing translational efforts. One of the major tasks for evaluators involved in translational research is to help assess efforts that aim to reduce the time it takes to move research to practice and health impacts. Another is to assess efforts that are intended to increase the rate and volume of translation. Methods: We offer an alternative to the dominant contemporary tendency to define translational research in terms of a series of discrete "phases." Results: We contend that this phased approach has been confusing and that it is insufficient as a basis for evaluation. Instead, we argue for the identification of key operational and measurable markers along a generalized process pathway from research to practice. Conclusions: This model provides a foundation for the evaluation of interventions designed to improve translational research and the integration of these findings into a field of translational studies. Clin Trans Sci 2011; Volume 4: 153-162