The burden of musculoskeletal diseases in the general population of Spain: results from a national survey
The burden of musculoskeletal diseases in the general population of Spain: results from a national survey
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DOI：
10.1136/ard.60.11.1040
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发表时间：
2001-11-01
影响因子：
27.4
通讯作者：
Laffon, A
中科院分区：
文献类型：
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作者：
Carmona, L;Ballina, J;Laffon, A
EPISER研究的目的是评估西班牙成年人群中类风湿性关节炎（RA）、腰痛、手和膝关节骨关节炎（OA）和纤维肌痛的患病率，并评估这些疾病对功能和生活质量的影响，以及卫生和社会资源的使用。采用分层多阶段整群抽样方法，从20个市（区）人口普查中随机抽取20岁以上的2998人。经过培训的风湿病学家进行结构化访问，询问受试者的风湿症状和社会人口学特征，完成经验证的功能测量工具（HAQ）和生活质量（SF-12），并进行标准化体检。病例定义由以前验证的标准。结果-估计患病率与95%的置信区间如下：RA终生累积：0.5%（0.3 - 0.9）;腰痛：14.8%（12.2 - 17.4）;症状性膝关节OA：10.2%（8.5 - 11.9）;手OA：6.2%（5.9 - 6.5）;纤维肌痛：2.4%（1.5 - 3.2）。大多数条件显着受损的功能和生活quality of life. Conclusions-EPISER研究的结果应用到成年西班牙人口的内部和外部效度。所研究的疾病影响了相当大比例的人口，对残疾和生活质量产生了不同程度的影响，导致大量的医生就诊、工作残疾和药物使用。
Objective-The objective of the EPISER study was to estimate the prevalence of rheumatoid arthritis (RA), low back pain, hand and knee osteoarthritis (OA), and fibromyalgia in the adult Spanish population, and to assess the impact of these diseases on function and quality of life, and use of health and social resources.Methods-2998 subjects aged 20 years or above were randomly selected by stratified multistage cluster sampling from the censuses of 20 municipalities. Trained rheumatologists carried out structured visits at which subjects were asked about rheumatic symptoms and sociodemographic characteristics, completed validated instruments for measuring function (HAQ) and quality of fife (SF-12), and underwent a standardised physical examination. Cases were defined by previously validated criteria.Results-The estimated prevalences with 95% confidence intervals were as follows: RA lifetime cumulative: 0.5% (0.3 to 0.9); low back pain: 14.8% (12.2 to 17.4); symptomatic knee OA: 10.2% (8.5 to 11.9); hand OA: 6.2% (5.9 to 6.5); fibromyalgia: 2.4% (1.5 to 3.2). Most conditions significantly impaired function and quality of life.Conclusions-The EPISER study has internal and external validity for application of the results to the adult Spanish population. The diseases studied affect a significant proportion of the population, with various degrees of impact on disability and quality of life resulting in a significant number of physician visits, work disability, and medication use.