Current Insights into the Modulation of Oral Bacterial Degradation of Dental Polymeric Restorative Materials.
Current Insights into the Modulation of Oral Bacterial Degradation of Dental Polymeric Restorative Materials.
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DOI：
10.3390/ma10050507
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发表时间：
2017-05-06
期刊：
影响因子：
--
通讯作者：
Melo MAS
中科院分区：
文献类型：
--
作者：
Zhang N;Ma Y;Weir MD;Xu HHK;Bai Y;Melo MAS
牙科用高分子复合材料因其美观性和与牙体的粘接性而成为窝洞充填的首选材料。然而，口腔被认为是聚合物材料的恶劣环境。口腔生物膜可降解聚合物组分，从而损害边缘完整性并导致龋齿复发。据报道，修复体周围的复发性龋是修复失败的主要原因。材料的降解大大影响了临床寿命。本文就口腔生物膜对树脂复合材料的降解过程、降解机制及其影响进行综述。此外，潜在的未来发展领域的树脂基牙科生物材料，重点是抗生物膜的策略也进行了审查。
Dental polymeric composites have become the first choice for cavity restorations due to their esthetics and capacity to be bonded to the tooth. However, the oral cavity is considered to be harsh environment for a polymeric material. Oral biofilms can degrade the polymeric components, thus compromising the marginal integrity and leading to the recurrence of caries. Recurrent caries around restorations has been reported as the main reason for restoration failure. The degradation of materials greatly compromises the clinical longevity. This review focuses on the degradation process of resin composites by oral biofilms, the mechanisms of degradation and its consequences. In addition, potential future developments in the area of resin-based dental biomaterials with an emphasis on anti-biofilm strategies are also reviewed.