Left ventricular untwisting rate by speckle tracking echocardiography

Left ventricular untwisting rate by speckle tracking echocardiography
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DOI:
10.1161/circulationaha.107.706770
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发表时间:
2007-11-27
期刊:
影响因子:
37.8
通讯作者:
Nagueh, Sherif F.
Nagueh, Sherif F.
中科院分区:
医学1区
文献类型:
--
作者:
Wang, Jianwen;Khoury, Dirar S.;Nagueh, Sherif F.

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最近的研究证实了斑点跟踪超声心动图测量左心室解扭率(UR)的有效性。一些报道表明,它可以提供额外的无创洞察左室舒张功能。方法与结果:对8只成年犬同时进行超声心动图成像和左室压测量(7F米勒导管)。腔静脉闭塞改变了小鼠的负荷状态,而多巴酚丁胺和艾司洛尔的输注改变了小鼠的松弛状态。下腔静脉阻塞在所有实验阶段(基线,多巴酚丁胺,艾司洛尔)导致显著降低(P
Background-Recent studies validated the measurement of left ventricular (LV) untwisting rate (UR) by speckle tracking echocardiography. A few reports suggest that it may provide additional noninvasive insight into LV diastolic function.Methods and Results-Simultaneous echocardiographic imaging and LV pressure measurements (7F Millar catheters) were performed in 8 adult dogs. Loading conditions were altered by caval occlusion, whereas lusitropic state was changed by dobutamine and esmolol infusion. Inferior vena cava occlusion at all experimental stages (baseline, dobutamine, esmolol) led to a significant decrease (P