MATERNAL MORTALITY ASSOCIATED WITH HYPERTENSIVE DISORDERS OF PREGNANCY IN AFRICA, ASIA, LATIN-AMERICA AND THE CARIBBEAN
MATERNAL MORTALITY ASSOCIATED WITH HYPERTENSIVE DISORDERS OF PREGNANCY IN AFRICA, ASIA, LATIN-AMERICA AND THE CARIBBEAN
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DOI：
10.1111/j.1471-0528.1992.tb13818.x
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发表时间：
1992-07-01
期刊：
影响因子：
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通讯作者：
DULEY, L
中科院分区：
文献类型：
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作者：
DULEY, L
目的介绍非洲、亚洲、拉丁美洲和加勒比地区与妊娠期高血压疾病相关的孕产妇死亡率估计数，并讨论预防这些死亡的策略。世界卫生组织产妇保健和安全孕产方案背景数据库。主要结局指标估计孕产妇总死亡率和与妊娠期高血压疾病相关的死亡比例。结果：非洲、拉丁美洲和加勒比地区与妊娠高血压疾病相关的死亡率估计值相似，尽管非洲的总死亡率要高得多。总体死亡率和与妊娠高血压疾病相关的差异在亚洲最大。尽管存在局限性，但这些数据表明，10-15%的孕产妇死亡与妊娠期高血压疾病有关，10%与子痫有关。在产妇死亡率相对较高的地方，过高的死亡率很可能是由于与出血和感染相关的死亡率很高，而降低产妇死亡率最有可能来自这些死亡的减少。来自发达国家和发展中国家的证据表明，与妊娠期高血压疾病有关的死亡是最难预防的。迫切需要对旨在预防这些死亡的干预措施进行更严格的评估。
Objective To present estimates of maternal mortality associated with hypertensive disorders of pregnancy in Africa, Asia, Latin America and the Caribbean, and to discuss strategies to prevent these deaths Design Retrospective review of all available data.Setting Database of the World Health Organization's Maternal Health and Safe Motherhood Programme.Main outcome measures Estimates of the total maternal mortality and the proportions of deaths associated with hypertensive disorders of pregnancy.Results Estimates of mortality associated with hypertensive disorders of pregnancy were similar in Africa, Latin America and the Caribbean, despite considerably higher total mortality in Africa. Variations in both overall mortality and that associated with hypertensive disorders of pregnancy were greatest in Asia. Despite their limitations, these data suggest that between 10-15% of maternal deaths are associated with hypertensive disorders of pregnancy, and that 10% are associated with eclampsia.Conclusions Where maternal mortality is relatively high, the excess is likely to be due to a high mortality associated with haemorrhage and infection and reductions are most likely to come from reductions in these deaths. Evidence from both developed and developing countries suggests that deaths associated with hypertensive disorders of pregnancy are the most difficult to prevent. More rigorous assessment of interventions designed to prevent these deaths is urgently required.