Early age of first sex: a risk factor for HIV infection among women in Zimbabwe
Early age of first sex: a risk factor for HIV infection among women in Zimbabwe
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DOI：
10.1097/01.aids.0000131338.61042.b8
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发表时间：
2004-07-02
期刊：
影响因子：
3.8
通讯作者：
Padian, NS
中科院分区：
文献类型：
--
作者：
Pettifor, AE;van der Straten, A;Padian, NS
目的：探讨津巴布韦城市女性性行为活跃的早期(15岁或以下)与HIV感染风险的关系。设计：对队列研究的筛查数据进行横断面分析。方法：从1999年11月至2002年9月在津巴布韦哈拉雷及周边地区的公共计划生育诊所招募18-35岁的性行为活跃女性。他们接受了简短的行为访谈和艾滋病毒检测。在接受筛查的4675名妇女中，4393名(94%)拥有完整的性行为和HIV血清状况资料，并纳入本次分析。首次性交的年龄中值为18岁，11.8%的女性报告在15岁或更早的时候经历过性行为。早年首次性交的女性有明显更高的风险，包括多个终生伴侣和没有完成高中学业。在二元广义线性回归模型中，在控制了性行为持续时间和当前年龄的情况下，首次性交早期报告的女性的HIV风险增加(相对风险为1.30；95%可信区间为1.13-1.50)；在控制了性伴数量等其他因素后，这种影响有所减弱。结论：我们的结果表明，早期首次性行为是该人群中HIV感染流行的显著预测因素，独立于其他已确定的因素。艾滋病毒预防战略应包括推迟首次性交的年龄，并应解决可能阻止年轻妇女这样做的障碍。(C)2004年Lippincott Williams Wilkins。
Objective: To explore the relationship between early age of coital debut (15 years of age or younger) and risk for HIV infection among sexually active urbanized Zimbabwean women.Design: Cross-sectional analysis of screening data from a cohort study.Methods: Sexually active women aged 18-35 years were recruited from public sector family planning clinics in and around Harare, Zimbabwe between November 1999 and September 2002. They received a brief behavioral interview and HIV testing. Of the 4675 women screened, 4393 (94%) had complete data on sexual behaviors and HIV serostatus, and were included in this analysis.Results: HIV prevalence in this sample was 40.1%. The median age of coital debut was 18 years and 11.8% of women reporting having experienced coital debut at age 15 or younger. Women with early coital debut had a significantly higher risk profile, including multiple lifetime partners and not completing high school. In binary generalized linear regression models HIV risk was increased for women reporting early age of coital debut (relative hazard, 1.30; 95% confidence interval, 1.13-1.50), controlling for duration of sexual activity and current age; this effect was attenuated somewhat after controlling for other factors such as number of sexual partners.Conclusions: Our results show that early coital debut is a significant predictor of prevalent HIV infection independent of other identified factors in this population. HIV prevention strategies should include delaying the age of first coitus and should address the barriers that may prevent young women from so doing.(C) 2004 Lippincott Williams Wilkins.