Normal cardiopulmonary responses during incremental exercise in 20- to 70-yr-old men.
Normal cardiopulmonary responses during incremental exercise in 20- to 70-yr-old men.
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20 至 70 岁男性增量运动期间的正常心肺反应。
DOI：
10.1249/00005768-199405000-00003
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发表时间：
1994
影响因子：
4.1
通讯作者：
R. Casaburi
中科院分区：
文献类型：
--
作者：
O. Inbar;A. Oren;M. Scheinowitz;A. Rotstein;R. Dlin;R. Casaburi
健康男性（N = 1424，年龄20-70岁）进行了渐进式递增平板运动试验，以达到最大意志。通过呼吸测量心脏变量。有氧运动能力（VO 2 max）以0.33 ml·kg-1的年平均速率下降。心率最大值下降0.685次·min-1·年-1，最大氧脉搏下降0.115 ml·次·kg-1·100。在最年轻（20-30岁）和最老（61-70岁）的几十年中，气体交换阈值（GET）分别为58%和69%，表示为VO 2 max的百分比。在整个年龄范围内，VE、Vt、f和PETCO 2的平均下降分别为29%、10%、21%和7%。VE/VO 2和VE/VECO 2从20-70岁分别增加了13%和14%，但PETO 2在50年内没有变化。身体（身高和体重）以及生活方式的特点（闲暇时间的活动，居住地，吸烟），被认为是有效的预测在大多数心肺值在最大的运动，因此应纳入预测方程等变量。在整个运动强度范围内，大多数心肺变量的正常反应模式被证明是受年龄影响的，因此应该在几十岁时进行标准化。
Healthy men (N = 1424, age 20-70 yr) underwent a progressive incremental treadmill exercise test to volitional maximum. Cardiopulmonary variables were measured breath-by-breath. The aerobic power (VO2max) declined at an average yearly rate of 0.33 ml.kg.-1min-1, HRmax declined 0.685 beats.min-1.yr-1, and max O2 pulse declined at an annual rate of 0.115 ml.beat-1.kg-1*100. Gas exchange threshold (GET) expressed as percentage of VO2max was 58% and 69% in the youngest (20-30 yr) and oldest (61-70 yr) decades, respectively. The average decline in VE, Vt, f, and PETCO2 over the entire age range was 29%, 10%, 21%, and 7%, respectively. There were increases in VE/VO2, and VE/VECO2, from age 20-70 yr of 13% and 14%, respectively, but no changes across 5 decades in PETO2. Physical (height and weight) as well as life-style characteristics (leisure time activity, place of residency, smoking), were found to be potent predictors in most of the cardiopulmonary values at maximal exercise and therefore should be incorporated in the predictive equations for such variables. Normal response patterns of most cardiopulmonary variables throughout the range of exercise intensities were shown to be age-affected and thus should be standardized for age decades.