A new mammalian period gene predominantly expressed in the suprachiasmatic nucleus
A new mammalian period gene predominantly expressed in the suprachiasmatic nucleus
复制标题
主要在视交叉上核表达的一个新的哺乳动物时期基因
作者：
T. Takumi;Chiaki Matsubara;Y. Shigeyoshi;Kouji Taguchi;K. Yagita;Y. Maebayashi;Yoko Sakakida;Ko Okumura;Naoyuki Takashima;H. Okamura
在哺乳动物中，最近报道了两种可能的时钟基因（Clock、Per1）。 mPer1（第一个鉴定的小鼠周期基因）尤其显示出在哺乳动物昼夜节律中心视交叉上核（SCN）中的昼夜节律表达。然而，仅使用 mPer1 和 Clock 作为时钟组件可能不足以理解昼夜节律振荡和夹带中的所有事件。
In mammals, two possible clock genes (Clock, Per1) have very recently been reported. mPer1 (the first identified mouse period gene), in particular, shows a circadian expression in suprachiasmatic nuclei (SCN), the mammalian circadian centre. However, only mPer1 and Clock as clock components may not be sufficient to understand all the events in circadian oscillation and entrainment.