Learning decision thresholds for risk stratification models from aggregate clinician behavior.
Learning decision thresholds for risk stratification models from aggregate clinician behavior.
复制标题
DOI:
10.1093/jamia/ocab159
复制
发表时间:
2021-09-18
期刊:
影响因子:
--
通讯作者:
Shah NH
中科院分区:
文献类型:
--
作者:
Patel BS;Steinberg E;Pfohl SR;Shah NH
Using a risk stratification model to guide clinical practice often requires the choice of a cutoff—called the decision threshold—on the model’s output to trigger a subsequent action such as an electronic alert. Choosing this cutoff is not always straightforward. We propose a flexible approach that leverages the collective information in treatment decisions made in real life to learn reference decision thresholds from physician practice. Using the example of prescribing a statin for primary prevention of cardiovascular disease based on 10-year risk calculated by the 2013 pooled cohort equations, we demonstrate the feasibility of using real-world data to learn the implicit decision threshold that reflects existing physician behavior. Learning a decision threshold in this manner allows for evaluation of a proposed operating point against the threshold reflective of the community standard of care. Furthermore, this approach can be used to monitor and audit model-guided clinical decision making following model deployment.
登录
查看更多内容
影响因子:
3.5
作者:
Attema, Arthur E.;Brouwer, Werner B. F.;l'Haridon, Olivier
通讯作者:
l'Haridon, Olivier
影响因子:
--
作者:
Habbema, JDF
通讯作者:
Habbema, JDF
影响因子:
3.6
作者:
EISENBERG, JM;HERSHEY, JC
通讯作者:
HERSHEY, JC
影响因子:
6.1
作者:
KAHNEMAN, D;TVERSKY, A
通讯作者:
TVERSKY, A
DOI:
10.1136/ebmed-2014-110140
发表时间:
2015-04-01
期刊:
Evidence-based medicine
影响因子:
--
作者:
Ebell, Mark H;Locatelli, Isabella;Senn, Nicolas
通讯作者:
Senn, Nicolas