Contrasting the use of 2 vision-specific quality of life questionnaires in subjects with open-angle glaucoma.
Contrasting the use of 2 vision-specific quality of life questionnaires in subjects with open-angle glaucoma.
复制标题
DOI：
10.1097/ijg.0b013e3181879e63
复制
发表时间：
2009-06
影响因子：
2
通讯作者：
CIGTS Study Group
中科院分区：
文献类型：
--
作者：
Wren PA;Musch DC;Janz NK;Niziol LM;Guire KE;Gillespie BW;CIGTS Study Group
比较青光眼初始合作治疗研究 (CIGTS) 中两种视觉特异性功能状态测量值以及临床参数。 CIGTS 参与者完成了视觉活动问卷 (VAQ) 和国家眼科研究所视觉功能问卷 (NEI-VFQ)，并接受了视野 (VF) 和视敏度 (VA) 测试。 426 名受试者在 54 个月时贡献了 VAQ 和 NEI-VFQ 分数。皮尔逊相关性用于评估关联性。评估明暗适应（平均值 = 66.1）、眩光残疾（66.4）和敏锐度/空间视力（67.7）的 VAQ 子量表（范围 0-100）表明 CIGTS 参与者发现最困难的视觉相关功能。在 NEI-VFQ 中，受试者报告了高水平的视觉功能，总分和 12 个分量表中的 9 个分量表的平均值≥90（满分 100）。一般视力（平均值=82.6）获得最低的子量表得分。两份问卷共有的两个分量表高度相关：VA (r=0.68) 和周边视力 (r=0.77)（均 p<.0001）。参与者的感知与视觉功能临床测量之间的相关性符合预期，但较弱。临床测量与 NEI-VFQ 之间的关联性比 VAQ 之间的关联性更强。较好的眼睛 VF 和较差的眼睛 VA 与受试者对其视觉功能的感知具有最多的显着相关性。 VF 损失的增加与两个问卷以及其他几个子量表的总体和周边视力子量表得分的显着下降相关。这些发现将帮助有兴趣评估患者视觉功能感知的研究人员在 VAQ 和 NEI-VFQ 之间做出明智的选择。
To compare two vision-specific functional status measures to each other and to clinical parameters in the Collaborative Initial Glaucoma Treatment Study (CIGTS). CIGTS participants completed the Visual Activities Questionnaire (VAQ) and the National Eye Institute-Visual Function Questionnaire (NEI-VFQ) and were tested for visual field (VF) and visual acuity (VA). 426 subjects contributed VAQ and NEI-VFQ scores at 54 months. Pearson correlations were used to assess associations. The VAQ subscales (range 0–100) that assessed light-dark adaptation (mean=66.1), glare disability (66.4), and acuity/spatial vision (67.7) indicated vision-related functions that CIGTS participants found most difficult. On the NEI-VFQ, subjects reported high levels of visual functioning, with mean ≥90 (out of 100) on the total score and in 9 of 12 subscales. General vision (mean=82.6) received the lowest subscale score. Two subscales common to both questionnaires were highly correlated: VA (r=0.68) and peripheral vision (r=0.77) (both p<.0001). Correlations between participants’ perceptions and clinical measures of visual function were in the expected direction, but weaker. Stronger associations were found between clinical measures and the NEI-VFQ than the VAQ. Better eye VF and worse eye VA had the highest number of significant correlations with subjects’ perceptions of their visual function. Increasing VF loss was associated with a significant decrease in the overall and peripheral vision subscale scores from both questionnaires, as well as several other subscales. These findings will help researchers interested in assessing patients’ perceptions of their visual function make an informed selection when choosing between the VAQ and the NEI-VFQ.