Stimulation of the GnRH pulse generator activity by continuous exposure to the male pheromones in the female goat
Stimulation of the GnRH pulse generator activity by continuous exposure to the male pheromones in the female goat
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DOI：
10.1262/jrd.45.243
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发表时间：
1999-08-01
影响因子：
1.8
通讯作者：
Mori, Yuji
中科院分区：
文献类型：
--
作者：
Ichimaru, Toru;Takeuchi, Yukari;Mori, Yuji
已知反刍动物物种如绵羊和山羊中的雄性信息素可以重新激活季节性不发情雌性的静止卵巢功能。我们以前已经表明，只有几分钟的暴露于雄性信息素可以加速GnRH脉冲发生器的活动立即在雌性山羊。在这项研究中，4h连续暴露于雄性信息素对GnRH脉冲发生器活动的影响，通过记录下丘脑内侧基底部的特定多单位活性（MUA）进行了检查。混合的雄鹿毛被用作雄性信息素的来源。6只切除卵巢的雌二醇致敏雌兔戴鼻罩8 h，在后4 h期间，将2.0 g合并的雄性毛发置于鼻罩喙端的腔室中。与只戴空面具时相比，暴露于男性头发的时间缩短（p
Male pheromones in ruminant species such as sheep and goats are known to reactivate quiescent ovarian function in seasonally anestrous females. We have previously shown that only a few minutes exposure to the male pheromone can accelerate the GnRH pulse generator activity immediately in the female goat. In this study the effect of 4 h continuous exposure to the male pheromone on the GnRH pulse generator activity was examined by recording the specific multiple unit acitivity (MUA) from the medial basal hypothalamus. Pooled buck hair was used as the source of male pheromone. Six ovariectomized estradiol-primed does were fitted with a nose-mask for 8 h, and during the latter 4 h period 2.0 g of pooled male hair was set in the chamber at the rostral end of the mask. As compared with the period when only an empty mask was put on, the exposure to the male hair resulted in a shortening (p