Bone marrow in children with acute lymphocytic leukemia: MR relaxation times.
Bone marrow in children with acute lymphocytic leukemia: MR relaxation times.
复制标题
急性淋巴细胞白血病儿童的骨髓：MR 弛豫时间。
作者：
S. G. Moore;C. Gooding;R. Brasch;R. Ehman;H. Ringertz;A. Ablin;K. Matthay;S. Zoger
对17例急性淋巴细胞白血病（ALL）患儿进行腰椎磁共振成像：8例为新诊断的ALL，4例为复发的ALL，5例为缓解期ALL。11名年龄匹配的儿童也被成像作为对照。计算所有儿童腰椎骨髓的T1和T2弛豫时间。骨髓的T1弛豫时间如下（平均值+/-标准差）：新诊断的ALL，968 msec +/- 68;复发的ALL，765 msec +/- 19;缓解的ALL，404 msec +/- 135;年龄匹配的对照，441 msec +/- 82。T1弛豫时间在区分初治ALL患儿与正常儿童和缓解期ALL患儿方面具有统计学意义。此外，T1可能有助于区分复发的ALL儿童与缓解的ALL儿童以及健康儿童。T2在四组之间没有显著差异。
Magnetic resonance imaging of the lumbar spine was performed in 17 children with acute lymphocytic leukemia (ALL): eight with newly diagnosed ALL, four with ALL in relapse, and five with ALL in remission. Eleven age-matched children were also imaged as controls. The T1 and T2 relaxation times of the bone marrow in the lumbar spine were calculated for all the children. The T1 relaxation times of the bone marrow were as follows (mean +/- standard deviation): newly diagnosed ALL, 968 msec +/- 68; ALL in relapse, 765 msec +/- 19; ALL in remission, 404 msec +/- 135; and age-matched controls, 441 msec +/- 82. T1 relaxation time was statistically significant in differentiating children with newly diagnosed ALL from normal children and from children with ALL in remission. In addition, T1 may be useful in differentiating children with ALL in relapse from children with ALL in remission and from healthy children. T2 was not significantly different among the four groups.