EFFECT OF GROUP SIZE, SEX AND TIME ON ORGAN WEIGHTS, CATECHOLAMINES AND BEHAVIOR IN MICE

EFFECT OF GROUP SIZE, SEX AND TIME ON ORGAN WEIGHTS, CATECHOLAMINES AND BEHAVIOR IN MICE
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DOI:
10.1016/0031-9384(69)90142-5
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发表时间:
1969-01-01
影响因子:
2.9
通讯作者:
ANTON, AH
ANTON, AH
中科院分区:
医学3区
文献类型:
--
作者:
ANTON, AH

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雄性和雌性小鼠被隔离和过度拥挤1周和4周,以确定[1],种群密度将对器官重量和儿茶酚胺与行为变化的关系产生什么影响,以及[2],什么方式可能会影响这些相互作用。唯一一致的显着的生理和生化效应是与性别有关的,不会因环境的变化而改变。然而,只有雄性小鼠才会出现与性别相关的打斗行为,这需要改变环境,即孤立,才能表现出来。因此,没有可测量的生化效应与行为的改变有关。
Male and female mice were subjected to isolation and excessive overcrowding for 1-week and 4-week periods to determine [1], what effect population density would have on organ weights and catecholamines in relationship to behavioral changes, and [2], in what manner time might influence these interactions. The only consistent significant physiologic and biochemical effects were sex-related and were not modified by changes in the environment. However, fighting behavior, a sex-related characteristic that was only elicited in the male mice, required a change in the environment, i.e. isolation, to be expressed. Thus, no measurable biochemical effect could be associated with a change in behavior.