PLACE UNITS IN HIPPOCAMPUS OF FREELY MOVING RAT
PLACE UNITS IN HIPPOCAMPUS OF FREELY MOVING RAT
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DOI：
10.1016/0014-4886(76)90055-8
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发表时间：
1976-01-01
影响因子：
5.3
通讯作者：
OKEEFE, J
中科院分区：
文献类型：
--
作者：
OKEEFE, J
在自由移动的大鼠海马CA1区记录单个单位。它们被分为位置单位、位移单位和其他单位。位置单位被定义为大鼠在迷宫中的位置是最大单位发射的必要条件的单位。当动物在一个地方嗅时，其中一些位置单位（错位单位）会最大限度地激发，因为它在那里发现了新的东西，或者没有找到通常在那里的东西。在与θ相关的行为期间，位移单元增加了它们的速率。海马慢波的活动。一般来说，这些行为改变了大鼠相对于环境的位置。各种环境操纵的影响（例如，关闭房间的灯）对位置单位的放电模式的影响，结果表明它们对简单的感觉刺激没有反应，也不对特定的运动行为有反应。部队被解雇也不可能纯粹是由于动机或激励因素。海马功能的认知地图理论得到了有力的支持。
Single units were recorded from the CA1 field of the hippocampus in the freely-moving rat. They were classified as place units, displace units or others. Place units were defined as those for which the rat''s position on the maze was a necessary condition for maximal unit firing. Some of these place units (misplace units) fired maximally when the animal sniffed in a place, either because it found something new there or failed to find something which was usually there. Displace units increased their rates during behaviors associated with .theta. activity in the hippocampal slow waves. In general these were behaviors which changed the rat''s position relative to the environment. The influence of various environmental manipulations (e.g., turning off the room lights) on the firing pattern of the place units was tested and the results suggest that they were not responding to a simple sensory stimulus nor to a specific motor behavior. Nor could the unit firing be due purely to motivational or incentive factors. The cognitive map theory of hippocampal function was strongly supported.