A new concept of brain lateralization from the function of the temporo-parietal junctions: Comment on “Left and right temporal-parietal junctions (TPJs) as “match/mismatch” hedonic machines: A unifying account of TPJ function” by Doricchi et al.
A new concept of brain lateralization from the function of the temporo-parietal junctions: Comment on “Left and right temporal-parietal junctions (TPJs) as “match/mismatch” hedonic machines: A unifying account of TPJ function” by Doricchi et al.
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来自颞顶叶连接处功能的大脑偏侧化的新概念：Doricchi 等人对“左右颞顶叶连接处 (TPJ) 作为“匹配/不匹配”享乐机器：对 TPJ 功能的统一说明”的评论。
DOI：
10.1016/j.plrev.2023.02.001
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发表时间：
2023
影响因子：
11.7
通讯作者：
Morioka Shu
中科院分区：
文献类型：
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作者：
瀬谷安弘;Morioka Shu
人类大脑通过最小化预测误差来形成自我和世界的稳定图像。这种大脑预测处理的理论是由Carl Friston提出的[1]。这一理论被称为自由能原理，认为当人类根据预测做出控制决策时，就会出现运动、感知、情感、认知和决策等人类心理现象。大脑的功能是根据自己的经验减少预测错误。大脑中的预测信号被称为传出副本，这个传出副本与顶叶中的实际感觉反馈进行比较。如果两个值之间的差异比阈值更显著，则将其定义为失配。然而，如果预测误差小，则脑-身体-环境信息之间的匹配稳定。Doricchi等人[2]认为颞顶连接（TPJ）负责这种匹配-失配信息处理。值得注意的是，左半球和右半球处理信息的方式不同。我认为这是一个基于TPJ功能的大脑偏侧化的新概念。从裂脑实验[3]中，左右脑功能的差异被称为侧化。这种现象在神经精神病学中已经广为人知。例如，Brain [4]报告了右顶叶损伤患者的视觉空间忽视。Broca [5]报道了左额下回损伤患者的失语症。随后，人们认识到语言是在包括左侧TPJ的额顶叶颞叶网络中处理的[6]。Doricchi等人[2]TPJ可能参与了过去的知识（即记忆）和正在进行的感官刺激（即这些信息之间的匹配-不匹配）之间的界面。至于让·皮亚杰的经典理论，他提倡一种学习过程，如果新信息与已知信息相匹配，则通过同化来增加知识，如果存在不匹配，则通过调节来增加知识。左侧TPJ可能参与了人脑的这些功能。左半球也参与工具操作。Buxbaum等人[7]报道，左下顶叶小叶负责工具操作的知识（手势痕迹）。Osiurak等人[8]提出，左下顶叶负责技术推理，例如根据其结构推断工具的使用，其功能障碍被描述为失用症。Pazzaglia等人[9]结果表明，失用症的病灶是左侧顶下小叶和左侧额下回。我们发现失用症是一种功能失调的整合，
The human brain forms stable images of the self and the world by minimizing prediction errors. This theory of predictive processing of the brain was proposed by Carl Friston [1]. This theory, called the free-energy principle, argues that human psychological phenomena such as movement, perception, emotion, cognition, and decision-making emerge when humans make control decisions based on predictions. The brain functions to reduce prediction errors based on one’s own experiences. The predictive signal in the brain is called the efference copy, and this efference copy is compared with the actual sensory feedback in the parietal lobe. If the discrepancy between the two values is more significant than a threshold value, it is defined as a mismatch. However, if the prediction error is small, the match between the brain-body-environment information is stable. Doricchi et al.[2] argued that the temporoparietal junction (TPJ) is responsible for this match-mismatch information processing. Notably, the left and right hemispheres process information differently. I believe that this is a new concept of brain lateralization based on TPJ function. From the split-brain experiment [3], the difference between the left and right brain functions was dubbed lateralization. This phenomenon was already well known in neuropsychiatry. For example, Brain [4] reported visuospatial neglect in patients with right parietal lobe injuries. Broca [5] reported aphasia in patients with left inferior frontal gyrus injuries. Subsequently, it was recognized that language is processed in a frontal-parietal-temporal network that includes the left TPJ [6]. Doricchi et al.[2] stated that the TPJ may be involved in the interface between past knowledge (ie, memory) and ongoing sensory stimuli (ie, the match-mismatch between such information). As for the classical theory by Jean Piaget, he advocated a learning process that increases knowledge by assimilation if new information matches known information and accommodation if a mismatch exists, thereby increasing knowledge. The left TPJ may be involved in these functions of the human brain. The left hemisphere is also involved in tool manipulation. Buxbaum et al.[7] reported that the left inferior parietal lobule is responsible for knowledge of tool manipulation (gestural engram). Osiurak et al.[8] suggested that the left inferior parietal lobule is responsible for technical reasoning such as inferring the use of a tool based on its structure, and that its dysfunction was described as apraxia. Pazzaglia et al.[9] showed that the foci of apraxia were the left inferior parietal lobule and the left inferior frontal gyrus. We showed that apraxia is a dysfunctional integration of