Cellular microbiology: can we learn cell physiology from microorganisms?

Cellular microbiology: can we learn cell physiology from microorganisms?
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细胞微生物学:我们可以从微生物中学习细胞生理学吗?

DOI:
10.1152/ajpcell.1999.276.4.c765
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发表时间:
1999
期刊:
The American journal of physiology
影响因子:
--
通讯作者:
Fasano,A
Fasano,A
中科院分区:
--
文献类型:
--
作者:
Fasano,A

文献摘要

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细胞微生物学是在细胞生物学和微生物学之间兴起的一门新学科。分子技术在细菌发病机制研究中的应用已经使一些发现成为可能,这些发现正在改变科学家看待细菌与宿主相互作用的方式。如今,对感染性腹泻病发病机制的分子基础的研究必然超越了细胞生物学、细菌学、肠道病理生理学和免疫学之间既定的界限。利用微生物病原体来解决细胞生理学问题现在刚刚产生了有前景的应用和惊人的结果。
Cellular microbiology is a new discipline that is emerging at the interface between cell biology and microbiology. The application of molecular techniques to the study of bacterial pathogenesis has made possible discoveries that are changing the way scientists view the bacterium-host interaction. Today, research on the molecular basis of the pathogenesis of infective diarrheal diseases of necessity transcends established boundaries between cell biology, bacteriology, intestinal pathophysiology, and immunology. The use of microbial pathogens to address questions in cell physiology is just now yielding promising applications and striking results.