Genetic conflict and sex chromosome evolution
Genetic conflict and sex chromosome evolution
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DOI：
10.1016/j.tree.2009.10.005
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发表时间：
2010-04-01
影响因子：
16.8
通讯作者：
Tao, Yun
中科院分区：
文献类型：
--
作者：
Meiklejohn, Colin D.;Tao, Yun
染色体性别决定系统为自私的遗传元件的进化创造了机会，这些遗传元件以牺牲其同源物为代价增加了一条性染色体的传递。由于性染色体上的这种自私元素会降低生育力并扭曲后代的性别比例，因此预期会进化出不连锁的抑制基因，从而使基因组的不同区域在性染色体的减数分裂传递方面发生冲突。在这里，我们认为，性染色体传递的经常性遗传冲突是一个重要的进化力量，形成了广泛的看似不同的现象，包括表观遗传调控的基因在种系中表达，基因组中的分布，和物种之间的杂交不育的进化。
Chromosomal sex determination systems create the opportunity for the evolution of selfish genetic elements that increase the transmission of one sex chromosome at the expense of its homolog. Because such selfish elements on sex chromosomes can reduce fertility and distort the sex ratio of progeny, unlinked suppressors are expected to evolve, bringing different regions of the genome into conflict over the meiotic transmission of the sex chromosomes. Here we argue that recurrent genetic conflict over sex chromosome transmission is an important evolutionary force that has shaped a wide range of seemingly disparate phenomena including the epigenetic regulation of genes expressed in the germline, the distribution of genes in the genome, and the evolution of hybrid sterility between species.