PERFORMANCES AND LIMITATIONS OF SEVERAL ULTRASOUND-BASED ELASTOGRAPHY TECHNIQUES: A PHANTOM STUDY
PERFORMANCES AND LIMITATIONS OF SEVERAL ULTRASOUND-BASED ELASTOGRAPHY TECHNIQUES: A PHANTOM STUDY
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DOI：
10.1016/j.ultrasmedbio.2017.06.008
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发表时间：
2017-10-01
影响因子：
2.9
通讯作者：
Correas, Jean-Michel
中科院分区：
文献类型：
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作者：
Franchi-Abella, Stephanie;Elie, Caroline;Correas, Jean-Michel
这项研究的目的是通过对校准的弹性成像体模进行体外测量来评估应变和剪切波(SW)弹性成像性能的准确性。采集是在一个模体上进行的，该模体包含4个包裹体(12-74kPa)，嵌入在均匀的背景材料(30kpa)中。我们对弹性图进行了定性评估，用每个包裹体与背景之间的应变或弹性比进行了半定量评估，并通过软件采集进行了定量评估。将比率和弹性估计值与期望值进行比较。计算偏差、相对误差和95%可信区间(95%CI)。所有技术都充分地将包裹体归类为比背景更硬或更软。对于僵硬比的估计，SW法比应变法更精确，并且正确分类测量的百分比明显更高(p=0.008)。尽管有恒定的偏差，但定量硬度测量是可重复性的。与应变方法相比，SW弹性成像方法提供了更多可重复性的组织硬度比估计，并且尽管存在恒定的偏差，但仍可重复性地定量组织硬度。(电子邮件：stephanie.frchi@affp.fr)(C)2017年世界医学和生物学超声联合会。
The objective of this study is to assess strain and shear wave (SW) elastography performance in terms of accuracy by performing in vitro measurements on a calibrated elastography phantom. Acquisitions were done on a phantom containing 4 inclusions (12-74 kPa) embedded in a homogeneous background material (30 kPa). We performed qualitative assessment on elastograms, semiquantitative assessment with strain or elasticity ratios between each inclusion and the background and quantitative evaluation with SW acquisitions. Ratio and elasticity estimations were compared with expected values. Biases, relative errors and 95% confidence intervals (95% CI) were calculated. All techniques adequately classified inclusions as harder or softer than the background. For stiffness ratio estimation, SW methods were more precise than strain methods and had significantly higher percentages of correctly classified measurements (p = 0.008). Quantitative stiffness measurements were reproducible despite constant biases. SW elastography methods provide more reproducible estimations of tissue stiffness ratio than strain methods, as well as reproducible quantitative tissue stiffness despite constant biases. (E-mail: stephanie.franchi@aphp.fr) (C) 2017 World Federation for Ultrasound in Medicine & Biology.