Visual prognosis in giant cell arteritis.
Visual prognosis in giant cell arteritis.
复制标题
巨细胞动脉炎的视觉预后。
DOI：
10.1016/s0161-6420(93)31608-8
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发表时间：
1993
期刊：
影响因子：
13.7
通讯作者：
Hunder,GG
中科院分区：
文献类型：
--
作者：
Aiello,PD;Trautmann,JC;McPhee,TJ;Kunselman,AR;Hunder,GG
目的：在巨细胞动脉炎（GCA）的视力预后进行了评价超过5yearperiods.Methods：作者回顾了所有患者的记录，诊断为GCA建立在马约诊所超过5年的时间，关于视力状况。5年后获得了这些患者的随访数据。结果：在研究的245名患者中，34名（14%）因GCA而永久失明。其中32例患者在开始糖皮质激素治疗GCA之前出现视力缺陷;另外2例患者在诊断和治疗开始后出现视力丧失。在开始口服糖皮质激素后，3名患者的视力丧失进展，另外5名患者的视力改善。5年后，开始口服糖皮质激素治疗后视力丧失的可能性被确定为1%（Kaplan-Meier技术），和额外的损失的可能性为13%，在GCA患者谁有视力缺陷的时间therapystarted.Conclusion：发展或进展的视力丧失是罕见的糖皮质激素治疗开始后。
Purpose:The visual prognosis in giant cell arteritis (GCA) was evaluated over a 5year period.Methods:The authors reviewed the records of all patients with a diagnosis of GCA established at the Mayo Clinic over a 5-year period regarding visual status. Follow-up data for these patients were obtained 5 years later.Results:Of the 245 patients studied, 34 (14%) permanently lost vision because of GCA. In 32 of these patients, the visual deficit developed before glucocorticoid therapy for GCA was begun; in the 2 other patients, the visual loss occurred after the diagnosis was made and therapy was started. Visual loss progressed in three patients after initiation of oral glucocorticoids, and in five other patients vision improved. After 5 years, the probability of loss of vision developing after initiating oral glucocorticoid treatment was determined to be 1 % (Kaplan-Meier technique), and the probability of additional loss was 13% in patients with GCA who had a visual deficit at the time therapy was begun.Conclusion:The development or progression of visual loss was rare after the initiation of glucocorticoid therapy.