Bone reactions at implants subjected to experimental peri-implantitis and static load - A study in the dog
Bone reactions at implants subjected to experimental peri-implantitis and static load - A study in the dog
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DOI：
10.1034/j.1600-051x.2002.290209.x
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发表时间：
2002-02-01
影响因子：
6.7
通讯作者：
Lindhe, J
中科院分区：
文献类型：
--
作者：
Gotfredsen, K;Berglundh, T;Lindhe, J
目的：研究种植体周组织对实验性粘膜炎或种植体周围侧向静载荷的反应。材料和方法：选用5只比格犬。拔除下颌前磨牙。12周后，在下颌骨每一象限植入3颗种植体。在一侧，种植体被设计成具有SLA表面，而在对侧，种植体被设计成翻转表面。启动了斑块控制程序。12周后，将中央和后部种植体与装有扩张螺丝的矫治器连接。在双侧前、后种植体颈部分别放置棉结扎线，终止菌斑控制措施。16周后，结扎被移除。术后8周不结扎，双侧扩张螺丝钉均激活。在12周的间隔中，每两周一次，重新启动螺钉。因此，每个表面组包括3个不同的实验部位：M组+L(粘膜炎+LOAD)，P组(种植体周围炎)，P组+L(种植体周炎+LOAD)。注射了荧光标记，并获得了标准化的X光照片。结果：侧向静载荷不能引起粘膜炎种植体周围骨丢失，也不能增加实验性种植体周围炎时种植体骨丢失。P+L组的骨标记率和界面区的骨密度均显著高于P组。结论：控制力的侧向静载荷对种植体的粘膜炎或种植体周围炎可能无不良影响。
Aim:The aim of the present experiment was to study peri‐implant tissue reactions to lateral static load at implants subjected to experimental mucositis or peri‐implantitis.Material and methods:5 beagle dogs were used. The mandibular premolars were extracted. After 12 weeks, 3 implants were installed in each quadrant of the mandible. In one side, the implants were designed with a SLA surface and in the contralateral side with a turned surface. A plaque control program was initiated. 12 weeks later, the central and posterior implants were connected with an appliance containing an expansion screw. Cotton ligatures were placed around the neck of the anterior and posterior implants in both sides, and the plaque control measures were terminated. Sixteen weeks later the ligatures were removed. After 8 weeks without ligatures, the expansion screws in both sides were activated. Once every 2 week during a 12‐week interval, the screws were reactivated. Thus, the model included 3 different experimental sites of each surface group: group M+L (mucositis+load); group P (peri‐implantitis); group P+L (peri‐implantitis+load). Fluorochrome labels were injected and standardized radiographs obtained. The animals were sacrificed and block biopsies of all implant sites dissected and prepared for histological analysis.Results:It was demonstrated that the lateral static load failed to induce peri‐implant bone loss at implants with mucositis and failed to enhance the bone loss at implants with experimental peri‐implantitis. The proportion of bone labels and the bone density in the interface zone were significantly higher in group P+L than in group P.Conclusion:It is suggested that a lateral static load with controlled forces may not be detrimental to implants exhibiting mucositis or peri‐implantitis.