Patterns of Depressive Symptoms and Social Relating Behaviors Differ Over Time From Other Behavioral Domains for Young People With Down Syndrome
Patterns of Depressive Symptoms and Social Relating Behaviors Differ Over Time From Other Behavioral Domains for Young People With Down Syndrome
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DOI：
10.1097/md.0000000000000710
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发表时间：
2015-05-01
期刊：
影响因子：
1.6
通讯作者：
Leonard, Helen
中科院分区：
文献类型：
--
作者：
Foley, Kitty-Rose;Bourke, Jenny;Leonard, Helen
与普通人群相比，智障人士经历行为、情感和精神问题的风险更高。据报道，唐氏综合症患者的行为问题比其他智障人士要少，但仍高于非智障人群(抑郁症和阿尔茨海默病除外)。本研究的目的是描述唐氏综合症青少年的行为分量表，包括抑郁症状、沟通障碍、焦虑、破坏性和社交能力。居住在西澳大利亚州珀斯的唐氏综合症青少年家庭参加了一项为期8年的问卷调查，时间跨度分别为2004年(n=255)、2009年(n=191)和2011年(n=188)。问卷收集了有关年轻人特征和家庭功能的信息。采用父母完成的成人发展行为量表(DBC-A)和初级照顾者版(DBC-P)测量情绪和行为问题。DBC得分从2004年到2011年下降，反映了自我专注行为的改善(系数-0.011，95%可信区间-0.031，-0.008)，焦虑(系数-0.009，95%CI-0.129，-0.006)，沟通障碍(系数-0.008，95%CI-0.012，-0.005)和扰乱/反社会行为(系数-0.013，95%CI-0.016，-0.009)分量表。抑郁症状和社交问题分量表下降幅度较小(系数-0.003，95%CI-0.007，-0.0001)(系数-0.003，95%CI-0.007，0.001)。据报道，与功能较高的人相比，功能较低的年轻人在每个子量表上都表现出明显更多的行为问题。患有唐氏综合症的年轻人的行为会随着时间的推移而改善，但抑郁症状和与社交相关的行为问题会一直持续到成年。那些有持续抑郁症状的人可能在成年后患抑郁症的风险很高。确定患有唐氏综合症的年轻人在成年后有患抑郁症的风险，这对预防和早期治疗具有重要意义。
People with intellectual disabilities are at a higher risk for experiencing behavioral, emotional, and psychiatric problems in comparison with the general population. People with Down syndrome have been reported as experiencing fewer behavioral problems than others with intellectual disability, although still at a greater level than the non-intellectually disabled population, except for depression and Alzheimer disease. The aim of this study was to describe the trajectories of subscales of behavior, including depressive symptoms, communication disturbance, anxiety, disruptiveness, and social relating abilities, for young adults with Down syndrome.Families of young adults with Down syndrome living in Perth, Western Australia, participated in a questionnaire study over 8 years, 2004 (n = 255), 2009 (n = 191), and 2011 (n = 188). Questionnaires collected information about young person characteristics and family functioning. The parent-completed Developmental Behavior Checklist-Adult (DBC-A) and Developmental Behavior Checklist-Primary Carer Version (DBC-P) were used to measure emotional and behavioral problems. These measures include the following subscales: disruptive, communication and anxiety disturbances, self-absorbed, antisocial, depressive, and social relating.DBC score declined from 2004 to 2011 reflecting an improvement in behavior in the self-absorbed (coeff -0.011, 95% confidence interval (CI) -0.031, -0.008), anxiety (coef -0.009 95% CI -0.129, -0.006), communication disturbances (coeff -0.008, 95% CI -0.012, -0.005) and disruptive/antisocial behavior (coeff -0.013, 95% CI -0.016, -0.009) subscales. Subscales for depressive symptoms and social relating problems decreased less (coeff -0.003, 95% CI -0.007, -0.0001) (coeff -0.003 95% CI -0.007, 0.001). Young people who were lower functioning were reported as exhibiting significantly more behavioral problems across every subscale when compared with those who were higher functioning.Behavior of young adults with Down syndrome improves over time but depressive symptoms and social relating behavior problems persist into adulthood. It is possible that those with persistent depressive symptoms are at a high risk for developing depressive illness in adulthood. Identifying young people with Down syndrome who are at risk for developing depression in adult life has implications for prevention and early treatment.