Long-term physical activity outcomes of home-based lifestyle interventions among breast and prostate cancer survivors
Long-term physical activity outcomes of home-based lifestyle interventions among breast and prostate cancer survivors
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DOI：
10.1007/s00520-011-1370-y
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发表时间：
2012-10-01
影响因子：
3.1
通讯作者：
Demark-Wahnefried, Wendy
中科院分区：
文献类型：
--
作者：
Ottenbacher, Allison J.;Day, R. Sue;Demark-Wahnefried, Wendy
很少有研究调查体力活动(PA)干预的长期影响。这项研究的目的是评估癌症幸存者在接受两项基于家庭的干预措施一年后，是否保持了中等到剧烈的体力活动(MVPA)水平的增加。Fresh Start试验随机将543名乳腺癌和前列腺癌患者随机分为两组：按顺序定制饮食和运动干预：顺序定制与标准化(注意力控制)。每个ARM在一年内收到八封邮件，并在一年和两年内进行随访。这项分析只关注了400名在基线时MVPA水平低于最佳水平的参与者(通过7天体力活动回忆来衡量)，并完成了为期2年的研究。在定制干预组中，基线、1年和2年随访的MVPA中值分钟分别为0、90和60分钟/周。注意对照组的相应数值分别为0、30和30min/周。从基线到两年随访，两组患者的MVPA均有显著改善(P<；0.01)。虽然在一年的随访中观察到了显著的臂间差异(p<；0.01)，但在两年的随访中只有一个趋势(p=0.08)。这项研究提供了证据，表明邮寄印记运动干预导致新诊断的癌症幸存者的MVPA显著和可持续的改善，这种改善在干预完成后很久才能观察到。虽然与标准化材料相比，量身定做的干预措施最初似乎在MVPA方面产生了更好的改善，但随着时间的推移，这些差异逐渐消失。
Few studies have investigated long-term effects of physical activity (PA) interventions. The goal of this study was to evaluate whether or not increased levels of moderate to vigorous physical activity (MVPA) were maintained by cancer survivors 1 year after receipt of two home-based interventions.The FRESH START trial randomized 543 breast and prostate cancer survivors to 1-of-2 mailed print diet and exercise interventions: sequentially-tailored vs. standardized (attention control). Each arm received eight mailings over a 1-year period, with follow-up at 1 and 2 years. This analysis focuses solely on the 400 participants who had suboptimal levels of MVPA at baseline (measured by the 7-Day Physical Activity Recall) and who completed the 2-year study.Median minutes of MVPA at baseline, 1-year and 2-year follow-up in the tailored intervention arm were as follows: 0, 90, and 60 min/week, respectively. The corresponding values in the attention control group were 0, 30, and 30 min/week. Significant improvements in MVPA from baseline to 2-year follow-up were observed in both study arms (p < 0.01). While significant between-arm differences were observed at 1-year follow-up (p < 0.01), there was only the suggestion of a trend (p = 0.08) at 2-year follow-up.This study provides evidence that mailed-print exercise interventions result in significant and sustainable improvements in MVPA among newly diagnosed cancer survivors that are observed well after the intervention is complete. While tailored interventions, as compared to standardized materials, appear to produce superior improvements in MVPA initially, these differences diminish over time.