Maintaining Blood Glucose Levels in Range (70-150 mg/dL) is Difficult in COVID-19 Compared to Non-COVID-19 ICU Patients-A Retrospective Analysis.
Maintaining Blood Glucose Levels in Range (70-150 mg/dL) is Difficult in COVID-19 Compared to Non-COVID-19 ICU Patients-A Retrospective Analysis.
复制标题
DOI：
10.3390/jcm9113635
复制
发表时间：
2020-11-12
影响因子：
3.9
通讯作者：
Rahman O
中科院分区：
文献类型：
--
作者：
Kapoor R;Timsina LR;Gupta N;Kaur H;Vidger AJ;Pollander AM;Jacobi J;Khare S;Rahman O
建议 COVID-19 感染患者出现 β 细胞功能障碍。 ICU 血糖控制不良与患者预后不良相关。这是对 2020 年 3 月 1 日至 4 月 30 日重症监护病房的 562 名患者进行的单中心回顾性分析。我们回顾了重症 COVID-19 患者和非 COVID-19 患者的时间范围 (70–150 mg/dL)，以及每日胰岛素使用情况。对 COVID-19 队列中的 93 名受试者和非 COVID-19 队列中的 469 名受试者进行了血糖 TIR (70–150 mg/dL) 百分比和平均每日胰岛素使用量的比较。与非 COVID-19 队列相比，COVID-19 队列花费的 TIR 显着减少（70-150 mg/dL）（44.4% vs. 68.5%）。 COVID-19 队列中每日平均胰岛素使用量较高（8.37 单位 vs 6.17 单位）。 ICU COVID-19 患者在范围 (70–150 mg/dL) 内花费的时间较短，并且需要较高的每日胰岛素剂量。对呼吸机的要求和呼吸机使用天数越高，TIR 越低。 TIR 较高的 COVID-19 患者死亡率较低。
Beta cell dysfunction is suggested in patients with COVID-19 infections. Poor glycemic control in ICU is associated with poor patient outcomes. This is a single center, retrospective analysis of 562 patients in an intensive care unit from 1 March to 30 April 2020. We review the time in range (70–150 mg/dL) spent by critically ill COVID-19 patients and non-COVID-19 patients, along with the daily insulin use. Ninety-three in the COVID-19 cohort and 469 in the non-COVID-19 cohort were compared for percentage of blood glucose TIR (70–150 mg/dL) and average daily insulin use. The COVID-19 cohort spent significantly less TIR (70–150 mg/dL) compared to the non-COVID-19 cohort (44.4% vs. 68.5%). Daily average insulin use in the COVID-19 cohort was higher (8.37 units versus 6.17 units). ICU COVID-19 patients spent less time in range (70–150 mg/dL) and required higher daily insulin dose. A higher requirement for ventilator and days on ventilator was associated with a lower TIR. Mortality was lower for COVID-19 patients who achieved a higher TIR.
登录
查看更多内容
影响因子：
82.9
作者：
Kuba K;Imai Y;Rao S;Gao H;Guo F;Guan B;Huan Y;Yang P;Zhang Y;Deng W;Bao L;Zhang B;Liu G;Wang Z;Chappell M;Liu Y;Zheng D;Leibbrandt A;Wada T;Slutsky AS;Liu D;Qin C;Jiang C;Penninger JM
通讯作者：
Penninger JM
影响因子：
7.3
作者：
Hamming, I;Timens, W;van Goor, H
通讯作者：
van Goor, H
影响因子：
8.9
作者：
Krinsley, JS
通讯作者：
Krinsley, JS
影响因子：
38.9
作者：
Philips, BJ;Meguer, JX;Baker, EH
通讯作者：
Baker, EH
影响因子：
5.8
作者：
Hrebícek, J;Janout, V;Cízek, L
通讯作者：
Cízek, L