Production of 2,3-butanediol from corncob molasses, a waste by-product in xylitol production
Production of 2,3-butanediol from corncob molasses, a waste by-product in xylitol production
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从木糖醇生产中的副产品玉米芯糖蜜生产 2,3-丁二醇
DOI：
10.1007/s00253-010-2557-8
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发表时间：
2010-07-01
影响因子：
5
通讯作者：
Xu, Ping
中科院分区：
文献类型：
--
作者：
Wang, Ailong;Wang, Yu;Xu, Ping
玉米芯糖蜜是木糖醇生产中的一种废弃副产品，含有高浓度的混合糖。本研究以玉米芯糖蜜为原料，利用肺炎克雷伯氏菌SDM发酵生产2，3-丁二醇。这是第一份关于利用玉米芯糖蜜生产散装化学品的报告。结果表明，K. pneumoniae SDM可以以优先方式利用玉米芯糖蜜中包含的各种糖：葡萄糖>阿拉伯糖>木糖。结果表明，高糖浓度对细胞生长和BD产生有抑制作用。补料分批发酵61 h后BD的最大浓度为78.9 g/l，BD生产率为1.3 g/l h，产率为81.4%。本研究表明，廉价的玉米芯糖蜜可以作为K. pneumoniae SDM，以及用于生产其他高价值化学品的潜在碳源。
Corncob molasses, a waste by-product in xylitol production, contains high concentrations of mixed sugars. In the present study, corncob molasses was used to produce 2,3-butanediol (BD) using Klebsiella pneumoniae SDM. This was the first report on the use of corncob molasses to produce bulk chemicals. Our results indicated that K. pneumoniae SDM can utilize various sugars contained in the corncob molasses in a preferential manner: glucose > arabinose > xylose. It was shown that high sugars concentration had an inhibitory effect on the cells growth and BD production. The maximum concentration of BD was 78.9 g/l after 61 h of fed-batch fermentation, giving a BD productivity of 1.3 g/l h and a yield of 81.4%. The present study suggests that the low-cost corncob molasses could be used as an alternative substrate for the production of BD by K. pneumoniae SDM, as well as a potential carbon source for production of other high-value chemicals.