Periodontal status of diabetics compared with nondiabetics: a meta-analysis
Periodontal status of diabetics compared with nondiabetics: a meta-analysis
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DOI：
10.1016/j.jdiacomp.2005.05.006
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发表时间：
2006-01-01
影响因子：
3
通讯作者：
Batayha, WQ
中科院分区：
文献类型：
--
作者：
Khader, YS;Dauod, AS;Batayha, WQ
背景资料：本荟萃分析通过比较糖尿病患者和非糖尿病患者牙周病的程度和严重程度来评估糖尿病与牙周病之间的关联。研究方法：使用MEDLINE数据库对1970年1月至2003年10月期间发表的研究进行文献检索，并手动检索相关研究中的参考文献。这项荟萃分析基于18项比较性横断面研究、3项前瞻性队列研究和2项临床试验的基线数据，这些临床试验比较了糖尿病患者和非糖尿病患者的口腔卫生、牙龈和牙周状况。纳入的研究中异质性明显，因此采用随机效应模型进行分析。结果如下：本研究显示糖尿病患者的平均菌斑指数（P11）、平均牙龈指数（GI）、平均牙周袋深度（PPD）和临床附着丧失（CAL）均显著低于对照组。然而，糖尿病患者有类似程度的口腔卫生，牙龈和牙周疾病的表面或网站的百分比与特定的分数P11，GI，探诊出血（BOP），PPD和CAL.Conclusions：糖尿病患者有一个显着较高的严重程度，但牙周疾病的程度相同，比非糖尿病患者。(c)2006年爱思唯尔公司All rights reserved.
Background: This meta-analysis was conducted to assess the association between diabetes mellitus and periodontal diseases by comparing the extent and severity of periodontal diseases between diabetics and nondiabetics. Methods: A literature search was performed using MEDLINE database for published studies from January 1970 through October 2003 with manual search for references in relevant studies. This meta-analysis was based on 18 comparative cross-sectional studies, three prospective cohort studies and baseline data of two clinical trials that compared oral hygiene, gingival and periodontal status between diabetics and nondiabetics. Heterogeneity was obvious among included studies; therefore, the analysis using random-effects model was conducted. Results: This study demonstrated that diabetics had significantly worse oral hygiene as measured by the average of plaque index (P11), higher severity of gingival disease as measured by the average of gingival index (GI) and higher severity of periodontal disease as measured by the average of probing pocket depth (PPD) and clinical attachment loss (CAL). However, diabetics had similar extent of oral hygiene, gingival and periodontal disease as measured by percentages of surfaces or sites with specific scores of P11, GI, bleeding on probing (BOP), PPD and CAL. Conclusions: Diabetics had a significantly higher severity but the same extent of periodontal disease than nondiabetics. (c) 2006 Elsevier Inc. All rights reserved.