Role of Flagella in the Pathogenesis of Helicobacter pylori.
Role of Flagella in the Pathogenesis of Helicobacter pylori.
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DOI：
10.1007/s00284-017-1256-4
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发表时间：
2017-07
影响因子：
2.6
通讯作者：
Gu H
中科院分区：
文献类型：
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作者：
Gu H
本文旨在探讨鞭毛幽门螺杆菌在人致病性中的作用。幽门螺杆菌是一种鞭毛状病原体，定植于人胃十二指肠黏膜并产生炎症，是胃肠道疾病的原因。其发病机制归因于定植和毒力因素。鞭毛幽门螺旋杆菌的主要功能是提供动力。我们认为鞭毛幽门螺杆菌在胃肠道粘膜的定植中起着重要的作用。因此，我们对鞭毛形态和运动的研究进行综述，探讨幽门螺旋杆菌鞭毛与致病性的关系。需要进一步调查以证实鞭毛与幽门螺杆菌致病性之间的关系。
This review aimed to investigate the role of Helicobacter pylori flagella on the pathogenicity of this bacterium in humans. Helicobacter pylori is a flagellated pathogen that colonizes the human gastroduodenal mucosa and produces inflammation, and is responsible for gastrointestinal disease. Its pathogenesis is attributed to colonization and virulence factors. The primary function of H. pylori flagella is to provide motility. We believe that H. pylori flagella play an important role in the colonization of the gastrointestinal mucosa. Therefore, we reviewed previous studies on flagellar morphology and motility in order to explore the relationship between H. pylori flagella and pathogenicity. Further investigation is required to confirm the association between flagella and pathogenicity in H. pylori.