Sentinel Surveillance for Pharyngeal Chlamydia and Gonorrhea Among Men Who Have Sex With Men-San Francisco, 2010
Sentinel Surveillance for Pharyngeal Chlamydia and Gonorrhea Among Men Who Have Sex With Men-San Francisco, 2010
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DOI：
10.1097/olq.0b013e3182495e2f
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发表时间：
2012-06-01
影响因子：
3.1
通讯作者：
Bernstein, Kyle T.
中科院分区：
文献类型：
--
作者：
Park, Jason;Marcus, Julia L.;Bernstein, Kyle T.
背景资料：虽然咽衣原体（CT）和淋病（GC）是一种潜在的重要传播途径，但关于男男性行为者（MSM）中咽衣原体和淋病负担的数据有限。方法：对2010年在旧金山弗朗西斯科筛查出的MSM进行咽部CT和GC检查。咽部CT和GC的患病率估计在5个哨点：市性病诊所，男同性恋者的健康诊所，艾滋病毒护理诊所，艾滋病毒检测点，和初级保健诊所由旧金山弗朗西斯科公共卫生部支持。结果：2010年共检测了12,454例咽部CT标本和12,457例咽部GC标本，总CT阳性率为1.69%（95% CI：1.47-1.93）和GC阳性率为5.76%（95% CI：5.36-6.19）。在5个哨点，咽部CT阳性率为1.10%（HIV检测点）~ 2.28%（性病门诊），咽部GC阳性率为3.4%（HIV检测点）~ 7.01%（性病门诊）。结论：哨点监测数据表明，弗朗西斯科MSM人群咽部CT和GC感染负担很大。咽部感染的识别和治疗可以防止这些细菌的持续传播。增加基于核酸扩增检测的咽部筛查的可及性应成为公共卫生的优先事项。
Background: Although a potentially important route for transmission, limited data exist on the burden of pharyngeal chlamydia (CT) and gonorrhea (GC) among men who have sex with men (MSM). We examined pharyngeal CT and GC among MSM screened in San Francisco in 2010.Methods: MSM seeking services in a variety of clinical settings provided clinician-collected pharyngeal specimens that were tested using the APTIMA Combo 2 platform. The prevalence of pharyngeal CT and GC was estimated at 5 sentinel sites: the municipal STD clinic, a gay men's health clinic, an HIV care clinic, an HIV testing site, and primary care clinics supported by the San Francisco Department of Public Health. Positivity for each infection was calculated as the number of positive tests divided by the number of testers with corresponding confidence intervals (CI).Results: In 2010, a total of 12,454 pharyngeal CT specimens and 12,457 pharyngeal GC specimens were tested for an overall CT positivity of 1.69% (95% CI: 1.47-1.93) and GC positivity of 5.76% (95% CI: 5.36-6.19). At the 5 sentinel sites, pharyngeal CT positivity ranged from 1.10% (HIV testing site) to 2.28% (STD clinic); pharyngeal GC positivity ranged from 3.4% (HIV testing site) to 7.01% (STD clinic).Conclusion: Sentinel surveillance data indicate that there is a substantial burden of pharyngeal CT and GC infections among MSM in San Francisco. Identification and treatment of pharyngeal infections could prevent ongoing transmission of these bacteria. Increasing access to nucleic acid amplification tests-based pharyngeal screening should be a public health priority.