Strategy for retreatment of therapeutic failure of eradication of Helicobacter pylori infection

Strategy for retreatment of therapeutic failure of eradication of Helicobacter pylori infection
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根除幽门螺杆菌感染治疗失败的再治疗策略

DOI:
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发表时间:
2001
影响因子:
4.1
通讯作者:
N. Sato
N. Sato
中科院分区:
医学3区
文献类型:
--
作者:
A. Nagahara;H. Miwa;R. Ohkura;Toshio Yamada;Kenji Sato;M. Hojo;N. Sato

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一种基于质子泵抑制剂(PPI)的三联疗法,由PPI、阿莫西林(A)和克拉霉素(C)或甲硝唑(M)组成,其根治率从80%到90%不等。然而,在一线治疗失败后,很少有关于最有效的方案来重新治疗患者的对照研究。因此,我们回顾了我们的经验,并比较了不同的抗菌药组合方案,以确定最佳的再治疗方案。
A proton pump inhibitor (PPI)‐based triple therapy consisting of a PPI, amoxicillin (A) and clarithromycin (C) or metronidazole (M) provides an eradication rate ranging from 80 to 90%. However, there have been few controlled studies with regard to the most effective regimen to re‐treat patients after failure of the first‐line therapy. Accordingly, we retrospectively reviewed our experiences and compared regimens with different combinations of antimicrobials to determine the optimal retreatment regimen.
DOI: 10.1016/0016-5085(92)90095-g
发表时间: 1992-02-01
期刊: GASTROENTEROLOGY
影响因子: 29.4
作者:
GRAHAM, DY;LEW, GM;GENTA, RM
通讯作者: GENTA, RM