Visuospatial properties of ventral premotor cortex
Visuospatial properties of ventral premotor cortex
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DOI：
10.1152/jn.1997.77.5.2268
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发表时间：
1997-05-01
影响因子：
2.5
通讯作者：
Gross, CG
中科院分区：
文献类型：
--
作者：
Graziano, MSA;Hu, XTA;Gross, CG
在猕猴腹侧运动前皮质，我们记录了对视觉和触觉刺激做出反应的神经元的活动。对于这些双峰细胞，视觉感受野从触觉感受野延伸到邻近的空间。他们的触觉感受场是按地形图组织的，手臂在内侧，脸在中间，嘴里在侧面。对许多神经元来说，视觉和触觉反应都是方向选择性的，尽管许多神经元也对静止刺激做出反应。在清醒的猴子中，有70%的双峰神经元在手臂上有触觉反应，当手臂移动时，视觉感受野发生移动。相比之下，对于0%的受试者，当眼睛或头部移动时，视觉接受野也会移动。因此，大多数“手臂+视觉”细胞的视觉感受野定位于神经，而不是眼睛或头部。在麻醉的猴子身上，手臂位置的影响是相似的。对于面部有触觉反应的双峰神经元，95%的视觉感受野随着头部的旋转而移动。相比之下，15%的受试者视觉感受野随眼睛移动，0%的受试者视觉感受野随手臂移动。因此，大多数“脸部+视觉”细胞的视觉感受野固定在头部，而不是眼睛或手臂。要构建一个固定在手臂上的视觉接受场，必须整合手臂、头部和眼睛的位置。对于ARM+视觉细胞，自发活动、视觉反应的大小，有时两者都受手臂(37%)、头部(75%)和眼睛(58%)的位置调节。相反，要构建一个固定在头部的视觉接受场，就必须使用眼睛的位置，而不是头部或手臂的位置。对于Face+视觉细胞，自发活动和/或反应大小受眼睛位置的影响(88%)，但不受头部或手臂位置的影响(0%)。固定在手臂上的视觉感受场可以将刺激位置编码在以手臂为中心的坐标中，这将有助于指导手臂的运动。同样，固定在头部的视觉感受野也可以在“以头部为中心”的坐标中对刺激进行编码，这对引导头部的运动很有用。63%的面部+视觉神经元在头部的自愿运动中做出反应。我们认为“以身体部位为中心”的坐标为感觉-运动整合问题提供了一种普遍的解决方案：感觉刺激位于固定在特定身体部位的坐标系中。
In macaque ventral premotor cortex, we recorded the activity of neurons that responded to both visual and tactile stimuli. For these bimodal cells, the visual receptive field extended from the tactile receptive field into the adjacent space. Their tactile receptive fields were organized topographically, with the arms represented medially, the face represented in the middle, and the inside of the mouth represented laterally. For many neurons, both the visual and tactile responses were directionally selective, although many neurons also responded to stationary stimuli. In the awake monkeys, for 70% of bimodal neurons with a tactile response on the arm, the visual receptive field moved when the arm was moved. In contrast, for 0% the visual receptive field moved when the eye or head moved. Thus the visual receptive fields of most ''arm + visual'' cells were anchored to the ann, not to the eye or head. In the anesthetized monkey, the effect of arm position was similar. For 95% of bimodal neurons with a tactile response on the face, the visual receptive field moved as the head was rotated. In contrast, for 15% the visual receptive field moved with the eye and for 0% it moved with the arm. Thus the visual receptive fields of most ''face + visual'' cells were anchored to the head, not to the eye or arm. To construct a visual receptive field anchored to the arm, it is necessary to integrate the position of the arm, head, and eye. For arm + visual cells, the spontaneous activity, the magnitude of the visual response, and sometimes both were modulated by the position of the arm (37%), the head (75%), and the eye (58%). In contrast, to construct a visual receptive field that is anchored to the head, it is necessary to use the position of the eye, but not of the head or the arm. For face + visual cells, the spontaneous activity and/or response magnitude was modulated by the position of the eyes (88%), but not of the head or the arm (0%). Visual receptive fields anchored to the arm can encode stimulus location in ''arm-centered'' coordinates, and would be useful for guiding arm movements. Visual receptive fields anchored to the head can likewise encode stimuli in ''head-centered'' coordinates, useful for guiding head movements. Sixty-three percent of face + visual neurons responded during voluntary movements of the head. We suggest that ''body-part-centered'' coordinates provide a general solution to a problem of sensory-motor integration: sensory stimuli are located in a coordinate system anchored to a particular body part.