2-dimethylarsinothioyl acetic acid identified in a biological sample: The first occurrence of a mammalian arsinothioyl metabolite
2-dimethylarsinothioyl acetic acid identified in a biological sample: The first occurrence of a mammalian arsinothioyl metabolite
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DOI：
10.1002/anie.200352740
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发表时间：
2004-01-01
影响因子：
16.6
通讯作者：
Feldmann, J
中科院分区：
文献类型：
--
作者：
Hansen, HR;Pickford, R;Feldmann, J
羊皮中的砷：报告了从生物来源（一种罕见的吃海藻的绵羊品种;见图）分离的硫代有机砷酸盐化合物（2-二甲基胂硫酰乙酸）的第一个特征。结果表明，哺乳动物的砷代谢比以前所声称的要复杂得多，这为有机硫代砷化合物的毒性提出了新的问题。
Arsenic in sheep's clothing: the first characterization of a thio-organoarsenate compound (2-dimethylarsinothioyl acetic acid) isolated from a biological source (a rare breed of seaweed-eating sheep; see picture) is reported. The result indicates that mammalian arsenic metabolism is much more complex than has been claimed before, which opens up new questions about the toxicity of such organoarsenothio(y)l compounds.