SOLUTE DIFFUSION IN SWOLLEN MEMBRANES .9. SCALING LAWS FOR SOLUTE DIFFUSION IN GELS
SOLUTE DIFFUSION IN SWOLLEN MEMBRANES .9. SCALING LAWS FOR SOLUTE DIFFUSION IN GELS
复制标题
DOI：
10.1002/app.1988.070360401
复制
发表时间：
1988-08-05
影响因子：
3
通讯作者：
PEPPAS, NA
中科院分区：
文献类型：
--
作者：
LUSTIG, SR;PEPPAS, NA
建立了球型和椭球型溶质在非多孔平衡膨胀水凝胶中扩散系数的标度规律。该定律将溶质扩散系数与溶质尺寸、凝胶网尺寸和凝胶平衡体积膨胀度联系起来。通过水凝胶（如聚乙烯醇、聚（2‐甲基丙烯酸羟乙酯）、纤维素等的膨胀网络）的低分子量和高分子量溶质扩散的适当数据验证了这一定律。一个额外的标度定律被开发出来，它与从平衡膨胀的水凝胶中释放小分子或大分子的速度与时间和聚合物网络的形态特征有关。
A scaling law was developed for the diffusion coefficient of spheroidal and ellipsoidal solutes in nonporous, equilibrium‐swollen hydrogels. The law relates the solute diffusion coefficient to the solute size, the gel mesh size, and the gel equilibrium volume degree of swelling. The law was verified by appropriate data of low and high molecular weight solute diffusion through hydrogels such as swollen networks of poly(vinyl alcohol), poly(2‐hydroxyethyl methacrylate), cellulose, and others. An additional scaling law was developed which relates the rate of release of a small or large molecule from an equilibrium swollen hydrogel with time and with morphological characteristics of the polymeric network.