Role of gammadelta T cells in protecting normal airway function.
Role of gammadelta T cells in protecting normal airway function.
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DOI：
10.1186/rr26
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发表时间：
2000-01-01
影响因子：
5.8
通讯作者：
Gelfand, E W
中科院分区：
文献类型：
--
作者：
Born, W K;Lahn, M;Gelfand, E W
自 15 年前被发现以来，γδ T 细胞的作用仍然有些难以捉摸。 γδ T 细胞的反应已在许多传染性和非传染性疾病中被发现。新证据表明，gammadelta T 细胞在气道中发挥着维持正常气道反应性或音调的功能。在肺部，不同的 γδ T 细胞亚群似乎具有特定的作用，一个亚群促进过敏性炎症，另一个亚群起到保护作用。
Since their discovery 15 years ago, the role of gammadelta T cells has remained somewhat elusive. Responses of gammadelta T cells have been found in numerous infectious and non-infectious diseases. New evidence points to gammadelta T cells' functioning in the airways to maintain normal airway responsiveness or tone. In the lung, distinct subsets of gammadelta T cell subsets seem to have specific roles, one subset promoting allergic inflammation, the other serving a protective role.