Wrist bone mineral density utility in diagnosing hip osteoporosis in postmenopausal women
Wrist bone mineral density utility in diagnosing hip osteoporosis in postmenopausal women
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DOI：
10.1177/2042018816658164
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发表时间：
2016-12-01
影响因子：
3.8
通讯作者：
Akbari, Masood Ghahvechi
中科院分区：
文献类型：
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作者：
Eftekhar-Sadat, Bina;Ghavami, Mostafa;Akbari, Masood Ghahvechi
背景：骨质疏松症是一种常见的骨骼疾病，随着年龄的增长而增加。腕骨骨密度(BMD)与其他骨骼部位有显著相关性，可作为骨质疏松的诊断方法。本研究旨在评价腕部骨密度在绝经后妇女骨质疏松症诊断中的作用。方法：对99名绝经后妇女进行横断面研究，年龄50~76岁，平均年龄57±6.9岁。采用双能X线骨密度仪(DXA)测量非优势腕、腰椎(L2~L4)和股骨的骨密度，同时拍摄腰椎侧位X线片评价退行性关节病(DJD)。结果：腕部骨量减少和骨质疏松发生率分别为40.4%和59.6%，髋部为38.4%和24.2%，腰椎骨密度为36.4%和49.5%。腕部骨密度与髋部骨密度呈正相关(r=0.468，p<；0.001)，腰部骨密度与腰椎骨密度呈正相关(r=0.322，p=0.001)。84例(84.8%)为腰椎X线所致DJD，其中轻度DJD 45例(53.5%)，中度DJD 33例(39.3%)，重度DJD 6例(7.2%)。结论：腕部BMD对绝经后妇女骨质疏松的诊断准确率高于腰椎BMD。
Background: Osteoporosis is a common bone disease that increases with age. Wrist bone mineral density (BMD) has significant correlation with other skeletal sites and it could be used as a diagnostic method for osteoporosis. The purpose of this study was to evaluate the role of wrist BMD in diagnosing osteoporosis in postmenopausal women.Methods: In this cross-sectional study, 99 postmenopausal women with mean age of 57 +/- 6.9 (range 50-76) years were evaluated. BMD of nondominant wrist, lumbar spine (L2-L4) and femur bone using a dual-energy X-ray absorptiometry (DXA) device as well as lateral lumbosacral X-ray for degenerative joint disease (DJD) evaluation were measured. Mean T-score of wrist was lower than hip and lumbar area.Results: Osteopenia and osteoporosis were observed in 40.4% and 59.6% in the wrist, 38.4% and 24.2% in the hip and 36.4% and 49.5% in lumbar-spine BMD measurements, respectively. There was positive correlation between wrist BMD with hip BMD (r = 0.468, p < 0.001) and lumbar BMD (r = 0.322, p = 0.001). DJD due to lumbosacral X-ray was reported in 84 cases (84.8%) including mild DJD in 45 (53.5%), moderate DJD in 33 (39.3%) and severe DJD in 6 (7.2%).Conclusions: Our results showed that wrist BMD has better accuracy than lumbar BMD in diagnosing osteoporosis in postmenopausal women.